PHR1683

セレコキシブ

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: セレコキシブ, 4-[5-(4-メチルフェニル)-3-(トリフルオロメチル)-1H-ピラゾール-1-イル]ベンゼンスルホンアミド, CJ-016377, CP-598107, PF-00345549, PHA-00846533, SC-58635, YM-177
• 実験式（ヒル表記法）: C₁₇H₁₄F₃N₃O₂S
• CAS番号: 169590-42-5
• 分子量: 381.37
• MDL番号: MFCD00941298
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823554
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to Ph. Eur. Y0001445; traceable to USP
• APIファミリー: celecoxib
• CofA: current certificate can be downloaded
• 包装: pkg of 1 g
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-30°C
• SMILES記法: Cc1ccc(cc1)-c2cc(nn2-c3ccc(cc3)S(N)(=O)=O)C(F)(F)F
• InChI: 1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
• InChI Key: RZEKVGVHFLEQIL-UHFFFAOYSA-N
• 遺伝子情報: human ... PTGS2(5743)

詳細

詳細

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

アプリケーション

Celecoxib may be used as a pharmaceutical reference standard for the determination of the analyte in wastewater samples and animal samples by various chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

セレコキシブは非ステロイド性抗炎症薬(NSAID)であり、シクロオキシゲナーゼ-2 (COX-2)の選択的阻害剤です。 COX-2に対するセレコキシブの選択性は、COX-1に対する選択性の少なくとも10～20倍になります。

アナリシスノート

このような2次標準は、入手可能な場合にはUSP、EP、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAC0274 in the slot below. This is an example certificate only and may not be the lot that you receive.

おすすめ製品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

安全性情報

• ピクトグラム: GHS08,GHS09
• シグナルワード: Danger
• 危険有害性情報: H360D,H373,H410
• 注意書き: P202 - P260 - P273 - P280 - P308 + P313 - P391
• 危険有害性の分類: Aquatic Chronic 1 - Repr. 1B - STOT RE 2
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable