PHR1638

アルフゾシン 塩酸塩

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: N-(3-((4-アミノ-6,7-ジメトキシ-2-キナゾリニル)メチルアミノ)プロピル)テトラヒドロ-2-フランカルボキサミド 塩酸塩, ウロザトラル 塩酸塩
• 実験式（ヒル表記法）: C₁₉H₂₇N₅O₄ · HCl
• CAS番号: 81403-68-1
• 分子量: 425.91
• MDL番号: MFCD00879135
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823527
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to Ph. Eur. A0325800; traceable to USP 1012917
• APIファミリー: alfuzosin
• CofA: current certificate can be downloaded
• 包装: ampule of 1 × 1 g
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-30°C
• SMILES記法: Cl.COc1cc2nc(nc(N)c2cc1OC)N(C)CCCNC(=O)C3CCCO3
• InChI: 1S/C19H27N5O4.ClH/c1-24(8-5-7-21-18(25)14-6-4-9-28-14)19-22-13-11-16(27-3)15(26-2)10-12(13)17(20)23-19;/h10-11,14H,4-9H2,1-3H3,(H,21,25)(H2,20,22,23);1H
• InChI Key: YTNKWDJILNVLGX-UHFFFAOYSA-N
• 遺伝子情報: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146)

詳細

詳細

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

アプリケーション

Alfuzosin hydrochloride may be used as a pharmaceutical reference standard for the quantification of alfuzosin hydrochloride levels in pharmaceutical formulations by reverse phase high-performance liquid chromatography (RP-HPLC), high performance thin layer chromatography (HPTLC) and spectrophotometry.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

塩酸アルフゾシンは前立腺肥大症(BPH)の治療に使用されるα-アドレナリン受容体遮断薬です。前立腺や膀胱頸部の筋弛緩作用によって排尿を改善します。

脚注

To see an example of a Certificate of Analysis for this material enter LRAA5304 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable