ABN998

Anti-phospho PSD95 Antibody (Thr19)

from rabbit, purified by affinity chromatography

• 別名: Disks large homolog 4, Postsynaptic density protein 95, PSD-95, Synapse-associated protein 90, SAP-90, SAP90
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: human
• 化学種の反応性（ホモロジーによる予測）: mouse (based on 100% sequence homology), rat (based on 100% sequence homology), bovine (based on 100% sequence homology)
• テクニック: immunohistochemistry: suitable (paraffin); inhibition assay: suitable (peptide); western blot: suitable
• NCBIアクセッション番号: NP_001122299
• UniProtアクセッション番号: P78352
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: phosphorylation (pThr19 )
• 遺伝子情報: human ... DLG4(1742)

詳細

詳細

PSD95 (postsynaptic density95) represent a class of anchoring proteins which serve to localize various neuronal ion channels to post-synaptic densities. PSD95 and related proteins contain PDZ domains, which interact with NMDA receptors and voltage-gated K+ channels via a ET/SXV motif in the cytoplasmic carboxyl terminus of the receptor channels.

免疫原

Epitope: Near N-Terminus

KLH-conjugated linear peptide corresponding to human phospho PSD95 (Thr19) near the N-Terminus.

アプリケーション

Research Category
ニューロサイエンス

Research Sub Category
発生シグナル伝達

Anti-phospho PSD95 Antibody (Thr19) is an antibody against phospho PSD95 (Thr19) for use in Western Blotting, Peptide Inhibition Assay, Immunohistochemistry (Paraffin).

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected phospho PSD95 (Thr19) in human cerebellum, human cerebral cortex, and human thalamus tissue.

品質

Evaluated by Western Blotting in human fetal brain tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected phospho PSD95 (Thr19) in 10 µg of human fetal brain tissue lysate.

ターゲットの説明

~80 kDa observed. The calculated molecular weight is 80 kDa, however phospho PSD95 (Thr19) has been shown as a ~80-95 kDa band in some western blots (Nelson, C.D., et al. (2013). J. of Neuroscience. 33(29):12122-12135).

物理的形状

Affinity

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

その他情報

Concentration: Please refer to lot specific datasheet.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable