218840

Caspase-8 Inhibitor II

InSolution

• 別名: InSolution Caspase-8 Inhibitor II, Granzyme B Inhibitor III; Z-IE(OMe)TD(OMe)-FMK
• 実験式（ヒル表記法）: C₃₀H₄₃FN₄O₁₁
• 分子量: 654.68
• UNSPSCコード: 12352200
• NACRES: NA.54

特性

• 品質水準: 100
• 形状: liquid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; desiccated (hygroscopic); protect from light
• 輸送温度: wet ice
• 保管温度: −20°C

詳細

詳細

A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO. Z-IETD-FMK is a potent, cell-permeable, and irreversible inhibitor of caspase-8 (MACH, FLICE, Mch5). Also inhibits granzyme B.

生物化学的／生理学的作用

Cell permeable: yes

Primary Target
caspase-8

Product does not compete with ATP.

Reversible: no

包装

Packaged under inert gas

警告

Toxicity: Irritant (B)

シーケンス

Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F*

物理的形状

A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO.

再構成

Following initial thaw, aliquot and freeze (-20°C).

アナリシスノート

≥98% (HPLC)

その他情報

Martin, D.A., et al. 1998. J. Biol. Chem.273, 4345.
Sweeney, E.A., et al. 1998. FEBS Lett.425, 61.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): 188.6 °F - (refers to pure substance)
• 引火点(℃): 87 °C - (refers to pure substance)