211275

Capsaicin

An active constituent of cayenne pepper with excitatory and desensitizing effects on a subset of primary afferent sensory neurons.

• 別名: Capsaicin, [(E)-N-(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide
• 実験式（ヒル表記法）: C₁₈H₂₇NO₃
• CAS番号: 404-86-4
• 分子量: 305.41
• MDL番号: MFCD00017259
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (TLC)
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: off-white
• 溶解性: ethanol: 5 mg/mL
• 輸送温度: ambient
• 保管温度: 10-30°C
• InChI: 1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
• InChI Key: YKPUWZUDDOIDPM-SOFGYWHQSA-N

詳細

詳細

An active constituent of cayenne pepper with excitatory and desensitizing effects on a subset of primary afferent sensory neurons. An antagonist of acetylcholine-induced responses in rat PC12 cells. Exhibits anti-nociceptive and anti-inflammatory effects. Inhibits NF-κB activation by TNF. Reversibly inhibits platelet aggregation.

An active constituent of cayenne pepper. Has excitatory and desensitizing effects on a subset of primary afferent sensory neurons. An antagonist of acetylcholine-induced respones in rat pheochromocytoma cells. Exhibits antinociceptive and anti-inflammatory effects. Inhibits NF-κB activation by TNF. Reversibly inhibits platelet aggregation.

警告

Toxicity: Toxic (F)

再構成

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

その他情報

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Singh, S., et al. 1996. J. Immunol.157, 4412.
Nakazawa, K., et al. 1994. Br. J. Pharmacol.113, 296.
Simmons, D.D., et al. 1994. Int. J. Dev. Neurosci.12, 517.
Takaki, M., et al. 1994. J. Mol. Cell. Cardiol.26, 1227.
Bevan, S., and Szolcsanyi, J. 1990. Trends Pharmacol. Sci.11, 330.
Pernow, B., et al. 1985. J. Immunol.135, 8125.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS06,GHS08,GHS05
• シグナルワード: Danger
• 危険有害性情報: H300,H315,H317,H318,H334,H335
• 注意書き: P261 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 2 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 引火点(°F): 235.4 °F - closed cup
• 引火点(℃): 113 °C - closed cup