204897

Complement C4b, Human

Complement C4b, Human, is a native, 193 kDa glycoprotein composed of the modified C4 α-chain (α′) and intact β- and γ-chains complement component.

• UNSPSCコード: 12352202
• NACRES: NA.25

特性

• 品質水準: 100
• アッセイ: ≥95% (SDS-PAGE)
• 形状: liquid
• 含まれません: preservative
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; avoid repeated freeze/thaw cycles
• 不純物: IgG, IgA, IgM, Factor B, Factor H, C3, ceruloplasmin, or albumin, trace
• 輸送温度: wet ice
• 保管温度: −70°C

詳細

生物化学的／生理学的作用

Complement C4b fragment is formed by the cleavage of the C4 α-chain by activated C1 enzyme. Like C3b, C4b has the transient ability to form a covalent ester bond with a variety of target cell surfaces. Target surface-bound C4b acts as an important non-enzymatic subunit of the classical pathway C3 cleaving enzyme (C4b, C2a). This surface-bound C4b also exhibits opsonic and immune adherence activities which are dependent on the CR1 (CD35) complement receptor found on many inflammatory cells.

ComplementC4b fragment is formed by the cleavage of the C4 α-chain by activated C1enzyme. Like C3b, C4b has the transient ability to form a covalent ester bond with a variety of target cell surfaces. Target surface-bound C4b acts as an important non-enzymatic subunit of the classical pathway C3 cleaving enzyme (C4b, C2a). This surface-bound C4b also exhibits opsonic and immune adherence activities which are dependent on the CR1 (CD35) complement receptor found on many inflammatory cells.

包装

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable