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BQ-788, Sodium Salt

• 別名: BQ-788, Sodium Salt, N- cis-2,6-Dimethylpiperidinocarbonyl-L-γ-MeLeu-D-Trp(MeOCO)-D-Nle-OH, Na
• 実験式（ヒル表記法）: C₃₄H₅₀N₅NaO₇
• 分子量: 663.78
• UNSPSCコード: 12352200
• NACRES: NA.28

特性

• アッセイ: ≥95% (HPLC)
• 品質水準: 100
• 形状: lyophilized solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; desiccated
• 色: white to off-white
• 溶解性: 0.01% NH₄OH: 1 mg/mL; DMSO: 2 mg/mL; methanol: water (3:1): 2 mg/mL
• 輸送温度: ambient
• 保管温度: −20°C

詳細

詳細

A highly selective and competitive ETB receptor antagonist (IC₅₀ = 1.2 nM).

Highly selective ET_B-receptor antagonist (IC₅₀ = 1.2 nM).

生物化学的／生理学的作用

Cell permeable: no

Primary Target
ETB-receptor antagonist

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 1.2 nM as ETB-receptor antagonist

警告

Toxicity: Standard Handling (A)

再構成

Following reconstitution, aliquot and freeze (-20°C). DMSO and Methano:H₂O stock solutions are stable for up to 2 months at -20°C.

その他情報

Okada, M., and Nishikibe, M. 2002. Cardiovasc. Drug Reviews20, 53.
Taniai, H., et al. 2001. Hepatology33, 894.
Fukuroda, T., et al. 1994. Biochem. Biophys. Res. Commun.199, 1461.
Ishikawa, K., et al. 1994. Proc. Natl. Acad. Sci. USA91, 4892.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable