927694

2-[6-(3-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}propoxy)pyridin-3-yl]acetic acid

≥95%

• 実験式（ヒル表記法）: C₁₉H₂₉N₃O₅
• 分子量: 379.45
• UNSPSCコード: 12352106

特性

• 品質水準: 100
• アッセイ: ≥95%
• 形状: powder
• 保管温度: 2-8°C

詳細

アプリケーション

2-[6-(3-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}propoxy)pyridin-3-yl]acetic acid is a heterobifunctional crosslinker useful for development of PROTAC degraders for targeted protein degradation or other bifunctional molecules in chemical biology. Incorporation of rigidity into the linker region may impact the 3D orientation of the molecules and thus ternary complex formation as well as optimization of drug-like properties. For linkers already conjugated to E3 ligase ligands, please visit our collection of Protein Degrader Building Blocks.

その他情報

Crosslinkers for Bioconjugation

Building PROTAC^® Degraders for Targeted Protein Degradation

Technology Article: Degrader Building Blocks for Targeted Protein Degradation

法的情報

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable