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Merck

TNNI1

troponin I type 1 (skeletal, slow)

別名:
SSTNI, TNN1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(7135) Summary: Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. [provided by RefSeq, Jul 2008]
  • Mouse(21952) troponin I, skeletal, slow 1
  • Rat(29388) troponin I type 1 (skeletal, slow)
  • cow(100301375) troponin I type 1 (skeletal, slow)
  • Goat(100860774) troponin I type 1 (skeletal, slow)
  • domestic guinea pig(100733717) troponin I type 1 (skeletal, slow)
  • naked mole-rat(101720739) troponin I type 1 (skeletal, slow)
  • chicken(421161) troponin I type 1 (skeletal, slow)
  • domestic cat(101096197) troponin I type 1 (skeletal, slow)
  • dog(100685160) troponin I type 1 (skeletal, slow)

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗心筋トロポニンI抗体 クローン1F23 ZooMAb®ウサギ・モノクローナル, recombinant, expressed in HEK 293 cells,
交差性
human, mouse, rat
アプリケーション
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot
Anti-TNNI1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-TNNI1 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
交差性
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat
アプリケーション
western blot
Anti-TNNI1 (AB1) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
Anti-Troponin I1/TnI1 Antibody, clone 5K1U2, Rabbit Monoclonal, ,
交差性
human, rat
アプリケーション
western blot

Proteins

製品番号
詳細
Species
Troponin1、Hisタグ融合 ヒト ヒト, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® Long Non-Coding esiRNA, targeting mouse TNNI1,
Species
mouse
MISSION® esiRNA, targeting human TNNI1,
Species
human