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Merck

SLX4

SLX4 structure-specific endonuclease subunit

別名:
BTBD12, FANCP, MUS312
Species:
UniProtKB ID:
遺伝子ID:
  • Human(84464) Summary: This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases.[provided by RefSeq, Jan 2011]
  • Mouse(52864) SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
  • Rat(302953) SLX4 structure-specific endonuclease subunit
  • Zebrafish(100001183) SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
  • Horse(100069533) SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
  • domestic cat(101095218) SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
  • chicken(416665) SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
  • dog(479867) SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
  • cow(512193) SLX4 structure-specific endonuclease subunit
  • sheep(101123086) SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
  • domestic guinea pig(100718161) SLX4 structure-specific endonuclease subunit
  • naked mole-rat(101709821) SLX4 structure-specific endonuclease subunit

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Antibodies

Product Number
詳細
交差性
アプリケーション
Anti-SLX4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-SLX4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry

esiRNA

Product Number
詳細
Species
MISSION® Long Non-Coding esiRNA, targeting human SLX4,
Species
human
MISSION® esiRNA, targeting mouse Slx4,
Species
mouse