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Merck

RRM2B

ribonucleotide reductase M2 B (TP53 inducible)

別名:
MTDPS8A, MTDPS8B, P53R2
Species:
UniProtKB ID:
遺伝子ID:
  • Human(50484) Summary: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
  • Mouse(382985) ribonucleotide reductase M2 B (TP53 inducible)
  • Rat(299976) ribonucleotide reductase M2 B (TP53 inducible)
  • cow(528960) ribonucleotide reductase M2 B (TP53 inducible)
  • sheep(101123639) ribonucleotide reductase M2 B (TP53 inducible)
  • naked mole-rat(101718446) ribonucleotide reductase M2 B (TP53 inducible)
  • domestic guinea pig(100715485) ribonucleotide reductase M2 B (TP53 inducible)
  • Zebrafish(368909) ribonucleotide reductase M2 b
  • chicken(420253) ribonucleotide reductase M2 B (TP53 inducible)
  • Horse(100062030) ribonucleotide reductase M2 B (TP53 inducible)
  • domestic cat(101099777) ribonucleotide reductase M2 B (TP53 inducible)
  • dog(481988) ribonucleotide reductase M2 B (TP53 inducible)

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-RRM2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
Anti-P53R2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-RRM2B antibody produced in mouse, clone 6C1, ascites fluid,
交差性
human
アプリケーション
ELISA
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
ヒドロキシ尿素, United States Pharmacopeia (USP) Reference Standard,
Species
human
ヒドロキシ尿素, European Pharmacopoeia (EP) Reference Standard,
Species
human
ヒドロキシ尿素, British Pharmacopoeia (BP) Reference Standard,
Species
human
ヒドロキシ尿素, 98%, powder,
Species
human
塩酸ゲムシタビン, ≥98% (HPLC),
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human RRM2B,
Species
human