コンテンツへスキップ
Merck

RNASEH2A

ribonuclease H2, subunit A

別名:
AGS4, JUNB, RNASEHI, RNHIA, RNHL
Species:
UniProtKB ID:
遺伝子ID:
  • Human(10535) Summary: The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009]
  • Mouse(69724) ribonuclease H2, large subunit
  • Rat(364974) ribonuclease H2, subunit A
  • Zebrafish(393195) ribonuclease H2, subunit A
  • domestic cat(101086121) ribonuclease H2, subunit A
  • dog(484925) ribonuclease H2, subunit A
  • cow(512830) ribonuclease H2, subunit A
  • sheep(101105746) ribonuclease H2, subunit A
  • Goat(100860936) ribonuclease H2, subunit A
  • domestic guinea pig(100715505) ribonuclease H2, subunit A
  • naked mole-rat(101714999) ribonuclease H2, subunit A

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

製品番号
詳細
交差性
アプリケーション
Monoclonal Anti-RNASEH2A antibody produced in mouse, clone 3G5-F5, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
Anti-RNASEH2A antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
immunofluorescence
western blot
Anti-RNASEH2A antibody produced in rabbit, IgG fraction of antiserum,
交差性
bovine, goat, horse, human, pig
アプリケーション
immunohistochemistry
western blot
Anti-RNASEH2A antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-RNASEH2A antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Rnaseh2a,
Species
mouse
MISSION® esiRNA, targeting human RNASEH2A,
Species
human