コンテンツへスキップ
Merck

RBPJ

recombination signal binding protein for immunoglobulin kappa J region

別名:
AOS3, CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH, csl
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3516) Summary: The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Also, this protein can bind specifically to the recombination signal sequence of immunglobulin kappa type J segments. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2011]
  • Mouse(19664) recombination signal binding protein for immunoglobulin kappa J region
  • Rat(679028) recombination signal binding protein for immunoglobulin kappa J region
  • chicken(422802) recombination signal binding protein for immunoglobulin kappa J region
  • Horse(100055547) recombination signal binding protein for immunoglobulin kappa J region
  • domestic cat(101100207) recombination signal binding protein for immunoglobulin kappa J region
  • dog(479122) recombination signal binding protein for immunoglobulin kappa J region
  • domestic guinea pig(100716535) recombination signal binding protein for immunoglobulin kappa J region
  • naked mole-rat(101726624) recombination signal binding protein for immunoglobulin kappa J region
  • cow(767928) recombination signal binding protein for immunoglobulin kappa J region
  • sheep(101107196) recombination signal binding protein for immunoglobulin kappa J region

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
詳細
交差性
アプリケーション
Anti-RBPJ antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-RBPJ Antibody, clone 2D10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human, mouse, rat
アプリケーション
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-RBP-Jk, clone 1F1 Antibody, clone 1F1, from rat,
交差性
drosophila, human
アプリケーション
ChIP
electrophoretic mobility shift assay

immunoprecipitation (IP)
Anti-RBPJ antibody produced in rabbit, affinity isolated antibody,
交差性
bovine, dog, guinea pig, horse, human, rabbit, rat
アプリケーション
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-RBP-Jk Antibody, Chemicon®, from rabbit,
交差性
human, mouse
アプリケーション
ChIP
immunohistochemistry

western blot

esiRNA

Product Number
詳細
Species
MISSION® esiRNA, targeting human RBPJ,
Species
human
MISSION® esiRNA, targeting mouse Rbpj,
Species
mouse