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Merck

PRKCZ

protein kinase C, zeta

別名:
PKC-ZETA, PKC2
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5590) Summary: Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(18762) protein kinase C, zeta
  • Rat(25522) protein kinase C, zeta
  • Domestic Rabbit(100009538) protein kinase C, zeta
  • naked mole-rat(101699303) protein kinase C, zeta
  • domestic guinea pig(100734946) protein kinase C, zeta
  • cow(286877) protein kinase C, zeta
  • sheep(101122295) protein kinase C, zeta
  • Zebrafish(555737) protein kinase C, zeta
  • chicken(419399) protein kinase C, zeta
  • domestic cat(101087851) protein kinase C, zeta
  • dog(479577) protein kinase C, zeta

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Antibodies

Product Number
詳細
交差性
アプリケーション
Anti-PRKCZ antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human, mouse
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Anti-PKC ζ antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-PKC ζ Antibody, clone 1F20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human
アプリケーション
ELISA
affinity binding assay

western blot
Anti-Phospho-PKC zeta-T560 antibody produced in rabbit, ,
交差性
human
アプリケーション
western blot
Anti-phospho-PKC ζ (pThr410) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
詳細
Species
UCN-01, ≥97% (HPLC), powder,
Species
human
GSK690693, ≥98% (HPLC),
Species
human

Proteins

Product Number
詳細
Species
プロテインキナーゼ Cζアイソザイム ヒト, ≥75% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution,
Species
human

esiRNA

Product Number
詳細
Species
MISSION® esiRNA, targeting human PRKCZ,
Species
human