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PATZ1

POZ (BTB) and AT hook containing zinc finger 1

別名:
MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG, dJ400N23
Species:
Human PATZ1 (23598), Mouse Patz1 (56218), Rat Patz1 (305471), Zebrafish patz1 (560290), domestic cat PATZ1 (101097426), cow PATZ1 (532416), Horse PATZ1 (100058375), dog PATZ1 (486365), chicken PATZ1 (416963), domestic guinea pig Patz1 (100730234) ...詳細
UniProtKB ID:
Q9HBE1, Q9HBE2, Q9HBE3, Q9P1A9, Q9UDU0, Q9Y529
遺伝子ID:
  • Human(23598) Summary: The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(56218) POZ (BTB) and AT hook containing zinc finger 1
  • Rat(305471) POZ (BTB) and AT hook containing zinc finger 1
  • Zebrafish(560290) POZ (BTB) and AT hook containing zinc finger 1
  • domestic cat(101097426) POZ (BTB) and AT hook containing zinc finger 1
  • cow(532416) POZ (BTB) and AT hook containing zinc finger 1
  • Horse(100058375) POZ (BTB) and AT hook containing zinc finger 1
  • dog(486365) POZ (BTB) and AT hook containing zinc finger 1
  • chicken(416963) POZ (BTB) and AT hook containing zinc finger 1
  • domestic guinea pig(100730234) POZ (BTB) and AT hook containing zinc finger 1
  • Domestic Rabbit(100328729) POZ (BTB) and AT hook containing zinc finger 1
  • naked mole-rat(101699786) POZ (BTB) and AT hook containing zinc finger 1
  • sheep(101115906) POZ (BTB) and AT hook containing zinc finger 1

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Antibodies

Product Number
詳細
交差性
アプリケーション
SAB2101726
抗PATZ1抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
bovine, dog, horse, human, mouse, rabbit, rat
アプリケーション
immunohistochemistry
western blot
HPA047893
抗PATZ1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

esiRNA

Product Number
詳細
Species
EHU233091
MISSION® Long Non-Coding esiRNA, targeting human PATZ1,
Species
human
EMU061981
MISSION® esiRNA, targeting mouse Patz1,
Species
mouse