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Merck

NR1I2

nuclear receptor subfamily 1, group I, member 2

別名:
BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR
Species:
UniProtKB ID:
遺伝子ID:
  • Human(8856) Summary: This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq, Jul 2008]
  • Mouse(18171) nuclear receptor subfamily 1, group I, member 2
  • Rat(84385) nuclear receptor subfamily 1, group I, member 2
  • Zebrafish(565875) nuclear receptor subfamily 1, group I, member 2
  • dog(403482) nuclear receptor subfamily 1, group I, member 2
  • cow(493713) nuclear receptor subfamily 1, group I, member 2
  • domestic cat(101088355) nuclear receptor subfamily 1, group I, member 2
  • domestic guinea pig(100719967) nuclear receptor subfamily 1, group I, member 2
  • naked mole-rat(101722589) nuclear receptor subfamily 1, group I, member 2
  • sheep(101118075) nuclear receptor subfamily 1, group I, member 2

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-NR1I2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-NR1I2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-NR1I2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-PXR Antibody, clone 1F10.1, clone 1F10.1, from mouse,
交差性
chimpanzee, gorilla, human
アプリケーション
western blot
抗NR1I2抗体 マウス宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human, rat
アプリケーション
immunofluorescence
western blot

Cell Lines

製品番号
詳細
Species
PXR Knockout HepaRG Cells, 1 vial,
Species

Proteins

製品番号
詳細
Species
プレグナンXレセプター ヒト, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Species
human
プレグナン Xレセプター (138-434)、Hisタグ融合 ヒト, recombinant, expressed in E. coli, ≥85% (SDS-PAGE),
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human NR1I2,
Species
human