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Merck

MMP2

matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

別名:
CLG4, CLG4A, MMP-II, MONA, TBE-1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(4313) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17390) matrix metallopeptidase 2
  • Rat(81686) matrix metallopeptidase 2
  • domestic guinea pig(100719361) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Domestic Rabbit(100009000) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • naked mole-rat(101696977) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • sheep(443115) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Zebrafish(337179) matrix metalloproteinase 2
  • chicken(386583) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • fruit fly(35997) Matrix metalloproteinase 2
  • cow(282872) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Horse(100033948) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • domestic cat(101098838) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • dog(403733) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

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ELISA

製品番号
詳細
Species
Human MMP-2 ELISA Kit, for serum, plasma, cell culture supernatant,
Species
human
Mouse MMP-2 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse
Rat MMP-2 ELISA, for serum, plasma and cell culture supernatants,
Species
rat

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-MMP-2 Antibody, a.a. 468-483 hMMP2, clone 42-5D11, clone 42-5D11, Chemicon®, from mouse,
交差性
bovine, horse, human, mouse, pig, rabbit, rat
アプリケーション
ELISA
immunohistochemistry

western blot
抗MMP2 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-MMP-2 (Ab-3) Mouse mAb (42-5D11), liquid, clone 42-5D11, Calbiochem®,
交差性
bovine, human, mouse, rat
アプリケーション
Anti-MMP-2 Antibody, pro and active form, clone VB3, clone VB3, Chemicon®, from mouse,
交差性
human
アプリケーション
ELISA
immunofluorescence

western blot
Anti- MMP2 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
マリマスタット, ≥98% (HPLC),
Species
human, rat, mouse
CP-101537, ≥98% (HPLC),
Species
human, rat, mouse
CP-471474, ≥98% (HPLC),
Species
human, rat, mouse
PD166793 水和物, ≥98% (HPLC),
Species
human, rat, mouse

Proteins

製品番号
詳細
Species
MMP-2 ヒト, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human
Matrix Metalloproteinase-2 ヒト, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
human
マトリックスメタロプロテアーゼ-2 マウス由来, recombinant, expressed in NSO cells, >95% (SDS-PAGE), buffered aqueous glycerol solution,
Species
mouse, rat

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Mmp2,
Species
mouse
MISSION® esiRNA, targeting human MMP2,
Species
human