MASP1
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
別名:
3MC1, CRARF, CRARF1, MAP1, MASP, MASP3, MAp44, PRSS5, RaRF
Species:
Human MASP1 (5648), Mouse Masp1 (17174), Rat Masp1 (64023), naked mole-rat Masp1 (101716867), domestic guinea pig Masp1 (100730575), sheep MASP1 (101111065), Zebrafish masp1 (100002060), cow MASP1 (522347), Horse MASP1 (100068261), domestic cat MASP1 (101097166) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(5648) Summary: This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
- Mouse(17174) mannan-binding lectin serine peptidase 1
- Rat(64023) mannan-binding lectin serine peptidase 1
- naked mole-rat(101716867) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- domestic guinea pig(100730575) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- sheep(101111065) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- Zebrafish(100002060) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- cow(522347) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- Horse(100068261) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- domestic cat(101097166) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- dog(488121) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- chicken(407088) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
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ELISA
Product Number
詳細
Species
Human CMASP-3 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human
Antibodies
Product Number
詳細
交差性
アプリケーション
抗MASP1抗体 ウサギ宿主抗体, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
抗MASP1抗体, affinity isolated antibody,
交差性
human, mouse
アプリケーション
immunohistochemistry
western blot
western blot
抗MASP1抗体 ウサギ宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
抗MASP1抗体 マウス宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
immunofluorescence
western blot
western blot
esiRNA
Product Number
詳細
Species