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Merck

KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

別名:
C-Kit, CD117, PBT, SCFR
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3815) Summary: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(16590) kit oncogene
  • Rat(64030) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • chicken(378783) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic cat(493766) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • cow(280832) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Horse(100009704) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • dog(403811) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Goat(100861386) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • sheep(780504) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Domestic Rabbit(100327263) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic guinea pig(100726397) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • naked mole-rat(101726400) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

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ELISA

製品番号
詳細
Species
Phosphotyrosine KIT / Mast/stem Cell Growth Factor Receptor Kit ELISA Kit, ,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-phospho-c-Kit (Tyr568/Tyr570) Antibody, Upstate®, from rabbit,
交差性
human
アプリケーション
western blot
Anti-C-KIT antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
western blot
Anti-CD117 (c-Kit) Antibody, clone 2C11, clone 2C11, from mouse,
交差性
human, mouse
アプリケーション
flow cytometry
western blot
Anti-CD117 Antibody, clone ACK2, clone ACK2, Chemicon®, from rat,
交差性
mouse
アプリケーション
flow cytometry
immunohistochemistry

immunoprecipitation (IP)

western blot
抗KIT ウサギ宿主抗体, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry

Small Molecule - Inhibitor

製品番号
詳細
Species
イマチニブ, ,
Species
human
ラゾパニブ, ,
Species
human
ダサチニブ, ≥98% (HPLC),
Species
human
ダサチニブ, ,
Species
human

Proteins

製品番号
詳細
Species
c-Kit Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant, human Kit, amino acids 544-end, for use in Kinase Assays.,
Species
human
c-Kit (D816V) Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant human c-Kit, amino acids 544-end containing the D816V mutation, for use in Kinase Assays.,
Species
human
cKit active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥32% (SDS-PAGE),
Species
human
c-KIT (D820E), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
c-KIT (N822K), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Kit,
Species
mouse
MISSION® esiRNA, targeting human KIT,
Species
human