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Merck

ITGAV

integrin, alpha V

別名:
CD51, MSK8, VNRA, VTNR
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
  • Mouse(16410) integrin alpha V
  • Rat(296456) integrin, alpha V
  • sheep(443143) integrin, alpha V
  • Domestic Rabbit(100008956) integrin, alpha V
  • domestic guinea pig(100728575) integrin, alpha V
  • naked mole-rat(101717672) integrin, alpha V
  • Zebrafish(100151255) integrin, alpha V
  • cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • Horse(100068706) integrin, alpha V
  • domestic cat(101085820) integrin, alpha V
  • dog(488437) integrin, alpha V
  • chicken(396420) integrin, alpha V

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Small Molecule - Antagonist

Product Number
詳細
Species
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
Species
human

Antibodies

Product Number
詳細
交差性
アプリケーション
抗インテグリンαVβ6抗体、クローン10D5、アジ化物フリー, clone 10D5, Chemicon®, from mouse,
交差性
human, mouse, rat
アプリケーション
flow cytometry
immunoprecipitation (IP)
Anti-Integrin αVβ3 Antibody, clone LM609, clone LM609, Chemicon®, from mouse,
交差性
avian, bovine, canine, chicken, human, monkey, pig, rabbit
アプリケーション
flow cytometry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)
Anti-Integrin αV Antibody, clone LM142, ascites fluid, clone LM142, Chemicon®,
交差性
human
アプリケーション
immunohistochemistry
immunoprecipitation (IP)
抗インテグリンαVβ3抗体、クローンLM609、アジ化物フリー, clone LM609, Chemicon®, from mouse,
交差性
avian, bovine, canine, chicken, human, monkey, pig, rabbit
アプリケーション
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Anti-Integrin αVβ5 Antibody, clone P1F6, clone P1F6, Chemicon®, from mouse,
交差性
chicken, human
アプリケーション
flow cytometry
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

Proteins

Product Number
詳細
Species
Human Integrin αVβ3, Octyl-β-D-glucopyranoside Formulation, ,
Species
human
Human Integrin αVβ3 Protein, Triton X-100 Formulation, ,
Species
human

esiRNA

Product Number
詳細
Species
MISSION® esiRNA, targeting mouse Itgav,
Species
mouse
MISSION® esiRNA, targeting human ITGAV,
Species
human