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Merck

IFIH1

interferon induced with helicase C domain 1

別名:
Hlcd, IDDM19, MDA-5, MDA5, RLR-2
Species:
UniProtKB ID:
遺伝子ID:
  • Human(64135) Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19. [provided by RefSeq, Jul 2012]
  • Mouse(71586) interferon induced with helicase C domain 1
  • Rat(499801) interferon induced with helicase C domain 1
  • chicken(424185) interferon induced with helicase C domain 1
  • dog(488371) interferon induced with helicase C domain 1
  • cow(535490) interferon induced with helicase C domain 1
  • Horse(100061257) interferon induced with helicase C domain 1
  • domestic cat(101099233) interferon induced with helicase C domain 1
  • sheep(101106234) interferon induced with helicase C domain 1
  • domestic guinea pig(100717607) interferon induced with helicase C domain 1
  • naked mole-rat(101721395) interferon induced with helicase C domain 1

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗MDA5/IFIH1抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
flow cytometry

immunohistochemistry

western blot
抗MDA5抗体 ウサギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-MDA-5 (Ser104), from rabbit, purified by affinity chromatography,
交差性
human
アプリケーション
inhibition assay
western blot
抗IFIH1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-MDA5 Antibody, from rabbit, purified by affinity chromatography,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human IFIH1,
Species
human
MISSION® esiRNA, targeting mouse Ifih1,
Species
mouse