コンテンツへスキップ
Merck

HP

haptoglobin

別名:
BP, HP2ALPHA2, HPA1S
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3240) Summary: This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(15439) haptoglobin
  • Rat(24464) haptoglobin
  • Zebrafish(566096) haptoglobin
  • fruit fly(251278) humped
  • dog(479668) haptoglobin
  • cow(280692) haptoglobin
  • domestic cat(100144610) haptoglobin
  • domestic guinea pig(100721435) haptoglobin
  • naked mole-rat(101705743) haptoglobin
  • sheep(101102413) haptoglobin
  • Domestic Rabbit(100008816) haptoglobin

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

製品番号
詳細
交差性
アプリケーション
抗ハプトグロビン ウサギ宿主抗体, IgG fraction of antiserum, lyophilized powder,
交差性
human
アプリケーション
ELISA
Anti-Haptoglobin antibody, Mouse monoclonal, clone HG-36, purified from hybridoma cell culture,
交差性
human
アプリケーション
ELISA
dot blot

immunoprecipitation (IP)

western blot
Anti-Haptoglobin (HP) antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
モノクロナール抗ハプトグロビン マウス宿主抗体, clone HG-36, ascites fluid,
交差性
human
アプリケーション
ELISA
抗HP抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
human
アプリケーション
immunohistochemistry
western blot

Proteins

製品番号
詳細
Species
ハプトグロビン ヒトプール血漿由来, ≥95% (SDS-PAGE), lyophilized powder,
Species
human
ハプトグロビン, ヒト, 表現型1-1, 98-100%, essentially salt-free, lyophilized powder,
Species
human
Haptoglobin (Phenotype 1-1) from human plasma, ≥95% (SDS-PAGE),
Species
human
Haptoglobin Plasma (MixedType) from human plasma, ≥95% (SDS-PAGE),
Species
human
Haptoglobin (Phenotype 2-2) from human plasma, ≥95% (SDS-PAGE),
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human HP,
Species
human