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Merck

HDAC1

histone deacetylase 1

別名:
GON-10, HD1, RPD3, RPD3L1
Species:
Human HDAC1 (3065), Mouse Hdac1 (433759), Rat Hdac1 (297893), Zebrafish hdac1 (192302), chicken HDAC1 (373961), dog HDAC1 (487309), domestic cat HDAC1 (101099228), cow HDAC1 (404126), domestic guinea pig Hdac1 (100728529), naked mole-rat Hdac1 (101715102)
UniProtKB ID:
Q13547, Q92534
遺伝子ID:
  • Human(3065) Summary: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
  • Mouse(433759) histone deacetylase 1
  • Rat(297893) histone deacetylase 1
  • Zebrafish(192302) histone deacetylase 1
  • chicken(373961) histone deacetylase 1
  • dog(487309) histone deacetylase 1
  • domestic cat(101099228) histone deacetylase 1
  • cow(404126) histone deacetylase 1
  • domestic guinea pig(100728529) histone deacetylase 1
  • naked mole-rat(101715102) histone deacetylase 1
  • sheep(100820752) histone deacetylase 1

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Activity Assay

Product Number
詳細
Species
CS1010
Histone Deacetylase Assay Kit, Fluorometric（ヒストン脱アセチル化アッセイキット、蛍光定量）, sufficient for 100 assays (96 well plates),
Species
human

Small Molecule - Antagonist

Product Number
詳細
Species
B103500
酪酸, ≥99%,
Species
human
W222119
酪酸, natural, ≥99%, FCC, FG,
Species
human
W222100
酪酸, ≥99%, FG,
Species
human
P6273
2-プロピルペンタン酸, ,
Species
rat, human, mouse

Antibodies

Product Number
詳細
交差性
アプリケーション
HPA029693
抗HDAC1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
western blot
AMAB90781
モノクローナル抗HDAC1抗体 マウス宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0510, purified immunoglobulin, buffered aqueous glycerol solution,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry
western blot
AV38530
抗HDAC1抗体 ウサギ宿主抗体, IgG fraction of antiserum,
交差性
bovine, dog, guinea pig, human, mouse, rat
アプリケーション
western blot
SAB5700004
Anti-HDAC1 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB4501383
Anti-HDAC1 antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
詳細
Species
SML0061
SAHA, ≥98% (HPLC),
Species
human
P6273
2-プロピルペンタン酸, ,
Species
rat, human, mouse
T8552
トリコスタチンA, ≥98% (HPLC), from Streptomyces sp.,
Species
human, mouse, rat
SML1175
ロミデプシン, ≥98% (HPLC),
Species
human
C0621
CI-994, ≥98% (HPLC), powder,
Species
human

Proteins

Product Number
詳細
Species
SRP0100
HDAC-1 human, recombinant, expressed in baculovirus infected insect cells, ≥50% (SDS-PAGE),
Species
human
SRP0101
HDAC 1 from Plasmodium falciparum, recombinant, expressed in baculovirus infected insect cells, ≥40% (SDS-PAGE),
Species
SRP5265
HDAC1, active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
詳細
Species
EHU025841
MISSION® esiRNA, targeting human HDAC1,
Species
human