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Merck

CRH

corticotropin releasing hormone

別名:
CRF
Species:
UniProtKB ID:
遺伝子ID:
  • Human(1392) Summary: Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010]
  • Mouse(12918) corticotropin releasing hormone
  • Rat(81648) corticotropin releasing hormone
  • chicken(404297) corticotropin releasing hormone
  • dog(486977) corticotropin releasing hormone
  • domestic cat(692345) corticotropin releasing hormone
  • cow(280755) corticotropin releasing hormone
  • sheep(101121525) corticotropin releasing hormone
  • Domestic Rabbit(100301553) corticotropin releasing hormone
  • domestic guinea pig(100719294) corticotropin releasing hormone
  • naked mole-rat(101717831) corticotropin releasing hormone

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Small Molecule - Agonist

製品番号
詳細
Species
アストレシン, ≥90% (HPLC),
Species
mouse, human, rat

Small Molecule - Antagonist

製品番号
詳細
Species
コルチコトロピン放出因子アンタゴニスト, ≥97% (HPLC),
Species
mouse, human, rat

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-CRH antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
western blot
Anti-CRH antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
Monoclonal Anti-CRH antibody produced in mouse, clone 2B11, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
抗副腎皮質刺激ホルモン放出因子 ウサギ宿主抗体, IgG fraction of antiserum, buffered aqueous solution,
交差性
bovine, canine, frog, human, mouse, pig, rat, sheep
アプリケーション
immunohistochemistry
microarray

radioimmunoassay

Proteins

製品番号
詳細
Species
コルチコトロピン放出因子 ヒト, ラット, ≥95% (HPLC), powder,
Species
human
Corticotropin Releasing Factor, Human and Rat, An immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla.,
Species
human
コルチコトロピン放出因子 ウシ, ≥90% (HPLC), Synthetic,
Species
cow
Corticotropin Releasing Factor Fragment 6-33 human, rat, ≥97% (HPLC),
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Crh,
Species
mouse
MISSION® esiRNA, targeting human CRH,
Species
human