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Merck

CLDN8

claudin 8

別名:
Species:
UniProtKB ID:
遺伝子ID:
  • Human(9073) Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.[provided by RefSeq, May 2010]
  • Mouse(54420) claudin 8
  • Rat(304124) claudin 8
  • Zebrafish(445278) claudin 8
  • chicken(427974) claudin 8
  • dog(478401) claudin 8
  • domestic cat(101096909) claudin 8
  • cow(538761) claudin 8
  • naked mole-rat(101707430) claudin 8
  • domestic guinea pig(100735357) claudin 8
  • sheep(101106811) claudin 8

Custom & Knockdown Gene Products

  • siRNA

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  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-CLDN8 (196-210) antibody produced in rabbit, IgG fraction of antiserum,
交差性
human
アプリケーション
western blot
Anti-CLDN8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-CLDN8 antibody produced in rabbit, IgG fraction of antiserum,
交差性
human
アプリケーション
immunohistochemistry
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human CLDN8,
Species
human