コンテンツへスキップ
Merck

CISH

cytokine inducible SH2-containing protein

別名:
BACTS2, CIS, CIS-1, G18, SOCS
Species:
Human CISH (1154), Mouse Cish (12700), Rat Cish (83681), Zebrafish cish (767678), chicken CISH (395335), dog CISH (484757), cow CISH (616753), domestic cat CISH (101096550), sheep CISH (101119259), naked mole-rat Cish (101716746)
UniProtKB ID:
Q9NSE2, B2R9N1, G5E9R1, Q9NS38, Q9Y5R1
遺伝子ID:
  • Human(1154) Summary: The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(12700) cytokine inducible SH2-containing protein
  • Rat(83681) cytokine inducible SH2-containing protein
  • Zebrafish(767678) cytokine inducible SH2-containing protein
  • chicken(395335) cytokine inducible SH2-containing protein
  • dog(484757) cytokine inducible SH2-containing protein
  • cow(616753) cytokine inducible SH2-containing protein
  • domestic cat(101096550) cytokine inducible SH2-containing protein
  • sheep(101119259) cytokine inducible SH2-containing protein
  • naked mole-rat(101716746) cytokine inducible SH2-containing protein
  • domestic guinea pig(100719354) cytokine inducible SH2-containing protein

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

製品番号
詳細
交差性
アプリケーション
SAB1400049
抗CISH抗体 マウス宿主抗体, IgG fraction of antiserum, buffered aqueous solution,
交差性
human
アプリケーション
immunofluorescence
western blot
HPA040812
抗CISH抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
SAB1400050
抗CISH抗体 ウサギ宿主抗体, IgG fraction of antiserum, buffered aqueous solution,
交差性
human
アプリケーション
immunofluorescence
western blot

esiRNA

製品番号
詳細
Species
EMU071861
MISSION® esiRNA, targeting mouse Cish,
Species
mouse
EHU079081
MISSION® esiRNA, targeting human CISH,
Species
human