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Merck

CHRM1

cholinergic receptor, muscarinic 1

別名:
HM1, M1, M1R
Species:
Human CHRM1 (1128), Mouse Chrm1 (12669), Rat Chrm1 (25229), cow CHRM1 (281684), Horse CHRM1 (100064117), domestic cat CHRM1 (101093801), domestic cat CHRM1 (493664), dog CHRM1 (483776), naked mole-rat Chrm1 (101702102), domestic guinea pig Chrm1 (100728041)
UniProtKB ID:
P11229
遺伝子ID:
  • Human(1128) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008]
  • Mouse(12669) cholinergic receptor, muscarinic 1, CNS
  • Rat(25229) cholinergic receptor, muscarinic 1
  • cow(281684) cholinergic receptor, muscarinic 1
  • Horse(100064117) cholinergic receptor, muscarinic 1
  • domestic cat(101093801) cholinergic receptor, muscarinic 1
  • domestic cat(493664) cholinergic receptor, muscarinic 1
  • dog(483776) cholinergic receptor, muscarinic 1
  • naked mole-rat(101702102) cholinergic receptor, muscarinic 1
  • domestic guinea pig(100728041) cholinergic receptor, muscarinic 1
  • sheep(101117029) cholinergic receptor, muscarinic 1

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Small Molecule - Agonist

Product Number
詳細
Species
PHR1493
ピロカルピン 塩酸塩, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
1538902
ピロカルピン 塩酸塩, United States Pharmacopeia (USP) Reference Standard,
Species
human
1539009
ピロカルピン 硝酸塩, United States Pharmacopeia (USP) Reference Standard,
Species
human
PHL80370
ピロカルピン 塩酸塩, phyproof® Reference Substance,
Species
human
P1650000
ピロカルピン 塩酸塩, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
詳細
Species
197602
キヌクリジン, 97%,
Species
rat
E5406
エトプロパジン 塩酸塩, ≥98% (HPLC), powder,
Species
human
PHR1470
スコポラミンヒドロブロミド, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
SML0847
Benztropine mesylate, ≥98% (HPLC),
Species
human
P7412
ピレンゼピン 二塩酸塩, ≥98% (TLC), powder,
Species
human

Antibodies

Product Number
詳細
交差性
アプリケーション
AB5164
Anti-Muscarinic Acetylcholine Receptor m1 Antibody, Chemicon®, from rabbit,
交差性
mouse, rat
アプリケーション
immunohistochemistry
western blot
HPA014101
Anti-CHRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
SAB4500244
Anti-CHRM1 antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
western blot
M9808
抗ムスカリン性アセチルコリンレセプター (M1) ウサギ宿主抗体, affinity isolated antibody, lyophilized powder,
交差性
mouse, rat
アプリケーション
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
詳細
Species
P127
(+)-ペンタゾシン, solid,
Species
rat, human
A8404
アミトリプチリン 塩酸塩, ≥98% (TLC), powder,
Species
human
D4526
ドキセピン 塩酸塩, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
Species
human
H1512
ハロペリドール, powder,
Species
human, rat
51330
ハルマリン, ≥95%,
Species
human, rat

Small Molecule - Ligand

Product Number
詳細
Species
A138
アミノベンズトロピン, solid,
Species
human

Proteins

Product Number
詳細
Species
HTS044M
ChemiScreen Membrane Preparation Human Recombinant M1 Muscarinic Acetylcholine Receptor, Human M1 GPCR membrane prepation for Radioligand binding Assays.,
Species
human
HTS044RTA
Ready-to-Assay M1 Acetylcholine (Muscarinic) Family Receptor Frozen Cells, ,
Species
human

esiRNA

Product Number
詳細
Species
EHU009821
MISSION® esiRNA, targeting human CHRM1,
Species
human