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Merck

CDKN2D

cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)

別名:
INK4D, p19, p19-INK4D
Species:
UniProtKB ID:
遺伝子ID:
  • Human(1032) Summary: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(12581) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
  • Rat(494444) similar to cyclin-dependent kinase inhibitor 2D
  • domestic guinea pig(100717134) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
  • naked mole-rat(101720531) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
  • sheep(101118528) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
  • dog(611216) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
  • domestic cat(101091765) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
  • cow(510244) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-CDKN2D antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Monoclonal Anti-p19INK4d antibody produced in mouse, clone DCS-100, ascites fluid,
交差性
human
アプリケーション
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

microarray

western blot
Monoclonal Anti-CDKN2D antibody produced in mouse, clone 2E10, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
ロスコビチン, ≥98% (TLC),
Species
human, mouse, rat
オロモウシン, ≥98% (HPLC),
Species
human, rat

Proteins

製品番号
詳細
Species
p19INK4D、GSTタグ融合 ヒト, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human CDKN2D,
Species
human
MISSION® esiRNA, targeting mouse Cdkn2d,
Species
mouse