CCR5
chemokine (C-C motif) receptor 5 (gene/pseudogene)
別名:
CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
Species:
Human CCR5 (1234), Mouse Ccr5 (12774), Rat Ccr5 (117029), chicken CCR5 (420695), dog CCR5 (484789), domestic cat CCR5 (493769), cow CCR5 (497017), Horse CCR5 (100048935), sheep CCR5 (101117453), Domestic Rabbit CCR5 (100101579) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(1234) Summary: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(12774) chemokine (C-C motif) receptor 5
- Rat(117029) chemokine (C-C motif) receptor 5
- chicken(420695) chemokine (C-C motif) receptor 5
- dog(484789) chemokine (C-C motif) receptor 5
- domestic cat(493769) chemokine (C-C motif) receptor 5
- cow(497017) chemokine (C-C motif) receptor 5
- Horse(100048935) chemokine (C-C motif) receptor 5
- sheep(101117453) chemokine (C-C motif) receptor 5
- Domestic Rabbit(100101579) chemokine (C-C motif) receptor 5
- naked mole-rat(101723738) chemokine (C-C motif) receptor 5
- domestic guinea pig(100716672) chemokine (C-C motif) receptor 5
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Small Molecule - Antagonist
製品番号
詳細
Species
Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-CCR5 (CD195) Antibody, clone HEK/1/85a/7a, clone HEK/1/85a/7a, from rat,
交差性
human
アプリケーション
flow cytometry
immunocytochemistry
immunocytochemistry
Anti-C-C Chemokine Receptor 5 Antibody, NT, Chemicon®, from rabbit,
交差性
human
アプリケーション
western blot
Monoclonal Anti-CD195-APC antibody produced in mouse, clone T21/8,
交差性
アプリケーション
flow cytometry
抗CCR5抗体 ウサギ宿主抗体, IgG fraction of antiserum, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CCR5, C-Terminal antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
ELISA
western blot
western blot