C2
complement component 2
別名:
CO2
Species:
Human C2 (717), Mouse C2 (12263), Rat C2 (24231), naked mole-rat C2 (101723809), domestic guinea pig C2 (100716184), sheep C2 (101115321), Domestic Rabbit C2 (100355553), chicken C2 (419574), cow C2 (515440), Horse C2 (100059162) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(717) Summary: Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.[provided by RefSeq, Mar 2009]
- Mouse(12263) complement component 2 (within H-2S)
- Rat(24231) complement component 2
- naked mole-rat(101723809) complement component 2
- domestic guinea pig(100716184) complement component 2
- sheep(101115321) complement component 2
- Domestic Rabbit(100355553) complement component 2
- chicken(419574) complement component 2
- cow(515440) complement component 2
- Horse(100059162) complement component 2
- domestic cat(101092434) complement component 2
- dog(474853) complement component 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
製品番号
詳細
交差性
アプリケーション
抗C2抗体 ウサギ宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
Anti-C2 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
交差性
dog, horse, human, mouse, pig, rat
アプリケーション
western blot
Proteins
製品番号
詳細
Species