コンテンツへスキップ
Merck

BAX

BCL2-associated X protein

別名:
BCL2L4
Species:
UniProtKB ID:
遺伝子ID:
  • Human(581) Summary: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12028) BCL2-associated X protein
  • Rat(24887) Bcl2-associated X protein
  • naked mole-rat(101713575) BCL2-associated X protein
  • domestic guinea pig(100730890) BCL2-associated X protein
  • Goat(100846984) BCL2-associated X protein
  • sheep(443059) BCL2-associated X protein
  • dog(403523) BCL2-associated X protein
  • domestic cat(493837) BCL2-associated X protein
  • cow(280730) BCL2-associated X protein

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Bax (NT) Antibody, from rabbit,
交差性
bovine, canine, chimpanzee, feline, human, rhesus monkey
アプリケーション
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Bax Antibody, NT, aa3-16 hBax protein, clone 2D2, clone 2D2, Chemicon®, from mouse,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

western blot
抗Bax抗体 クローン1C7 ZooMAb® ウサギ・モノクローナル, recombinant, expressed in HEK 293 cells,
交差性
human
アプリケーション
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot
Anti-BAX antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
immunoprecipitation (IP)

western blot
Monoclonal Anti-BAX antibody produced in mouse, clone 1F5-1B7, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

proximity ligation assay

western blot

Cell Lines

製品番号
詳細
Species
SW48細胞BAX -/-, ,
Species
human
DLD1細胞BAX -/-, ,
Species
human
DLD1細胞BAX/BAK(-/-,-/-), ,
Species
human
SW48細胞BAX/BAK(-/-,-/-), ,
Species
human

Proteins

製品番号
詳細
Species
BAX、GSTタグ融合 ヒト, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human BAX,
Species
human