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Merck

BAP1

BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)

別名:
HUCEP-13, UCHL2
Species:
Human BAP1 (8314), Mouse Bap1 (104416), Rat Bap1 (306257), Zebrafish bap1 (558885), cow BAP1 (100124510), Horse BAP1 (100051934), domestic cat BAP1 (101092671), dog BAP1 (484737), chicken BAP1 (415944), Thale Cress BAP1 (825291) ...詳細
UniProtKB ID:
Q92560, A8K993, Q6LEM0, Q7Z5E8
遺伝子ID:
  • Human(8314) Summary: This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013]
  • Mouse(104416) Brca1 associated protein 1
  • Rat(306257) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • Zebrafish(558885) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • cow(100124510) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • Horse(100051934) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • domestic cat(101092671) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • dog(484737) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • chicken(415944) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • Thale Cress(825291) BON association protein 1
  • naked mole-rat(101703932) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • domestic guinea pig(100731081) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • sheep(101111666) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)

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Antibodies

Product Number
詳細
交差性
アプリケーション
HPA055560
抗BAP1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
PLA0248
Rabbit anti-BAP1 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
交差性
human
アプリケーション
immunoprecipitation (IP)
western blot
SAB1406654
抗BAP1抗体 マウス宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
immunofluorescence
western blot
HPA028815
抗BAP1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence

esiRNA

Product Number
詳細
Species
EMU031191
MISSION® esiRNA, targeting mouse Bap1,
Species
mouse
EHU012991
MISSION® esiRNA, targeting human BAP1,
Species
human