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Merck

APEX1

APEX nuclease (multifunctional DNA repair enzyme) 1

別名:
APE, APE1, APEN, APEX, APX, HAP1, REF1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(328) Summary: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008]
  • Mouse(11792) apurinic/apyrimidinic endonuclease 1
  • Rat(79116) APEX nuclease (multifunctional DNA repair enzyme) 1
  • Zebrafish(406730) APEX nuclease (multifunctional DNA repair enzyme) 1
  • cow(281630) APEX nuclease (multifunctional DNA repair enzyme) 1
  • domestic cat(101101318) APEX nuclease (multifunctional DNA repair enzyme) 1
  • dog(482558) APEX nuclease (multifunctional DNA repair enzyme) 1
  • chicken(100431102) APEX nuclease (multifunctional DNA repair enzyme) 1
  • Goat(100860967) APEX nuclease (multifunctional DNA repair enzyme) 1
  • sheep(101115462) APEX nuclease (multifunctional DNA repair enzyme) 1
  • naked mole-rat(101709711) APEX nuclease (multifunctional DNA repair enzyme) 1
  • domestic guinea pig(100719062) APEX nuclease (multifunctional DNA repair enzyme) 1

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Antibodies

Product Number
詳細
交差性
アプリケーション
抗APEX1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Anti-APEX1 antibody produced in rabbit, ,
交差性
human
アプリケーション
immunofluorescence
immunoprecipitation (IP)

western blot
Monoclonal Anti-APEX1 antibody produced in mouse, clone 4D1, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
抗APEX1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Monoclonal Anti-APEX1 antibody produced in mouse, clone 3E12, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunoprecipitation (IP)

esiRNA

Product Number
詳細
Species
MISSION® esiRNA, targeting human APEX1,
Species
human
MISSION® esiRNA, targeting mouse Apex1,
Species
mouse