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Merck

ACLY

ATP citrate lyase

別名:
ACL, ATPCL, CLATP
Species:
UniProtKB ID:
遺伝子ID:
  • Human(47) Summary: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(104112) ATP citrate lyase
  • Rat(24159) ATP citrate lyase
  • chicken(395373) ATP citrate lyase
  • Horse(100053195) ATP citrate lyase
  • cow(511135) ATP citrate lyase
  • domestic cat(100422779) ATP citrate lyase
  • dog(607852) ATP citrate lyase
  • naked mole-rat(101700349) ATP citrate lyase
  • domestic guinea pig(100714933) ATP citrate lyase
  • sheep(654404) ATP citrate lyase

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-ACLY, clone 5F8D11 Antibody, clone 5F8D11, from mouse,
交差性
human, monkey, mouse
アプリケーション
ELISA
flow cytometry

immunofluorescence

immunohistochemistry

western blot
Anti-ACLY antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Anti-ATP-citrate synthase/ACLY Antibody, from rabbit, purified by affinity chromatography,
交差性
bovine, human, mouse, porcine, rat, sheep
アプリケーション
immunohistochemistry
western blot
Anti-ACLY Antibody, clone 1B16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human, mouse, rat
アプリケーション
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-ACLY antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot

Proteins

製品番号
詳細
Species
ATP Citrate Lyase Active human, recombinant, expressed in baculovirus, ≥90% (SDS-PAGE),
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Acly,
Species
mouse
MISSION® esiRNA, targeting human ACLY,
Species
human