ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
別名:
ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11
Species:
Human ABCC5 (10057), Mouse Abcc5 (27416), Rat Abcc5 (116721), sheep ABCC5 (101123431), Domestic Rabbit ABCC5 (100351084), naked mole-rat Abcc5 (101718472), domestic guinea pig Abcc5 (100723026), Zebrafish abcc5 (336147), cow ABCC5 (511769), Horse ABCC5 (100066941) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(10057) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected; however, the complete sequence and translation initiation site is unclear. [provided by RefSeq, Jul 2008]
- Mouse(27416) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- Rat(116721) ATP-binding cassette, subfamily C (CFTR/MRP), member 5
- sheep(101123431) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- Domestic Rabbit(100351084) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- naked mole-rat(101718472) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- domestic guinea pig(100723026) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- Zebrafish(336147) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- cow(511769) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- Horse(100066941) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- domestic cat(101090542) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- chicken(424947) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- dog(478648) ATP-binding cassette, sub-family C (CFTR/MRP), member 5
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Antibodies
製品番号
詳細
交差性
アプリケーション
抗ABCC5抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
抗ABCC5抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Monoclonal Anti-ABCC5 antibody produced in mouse, clone 1B12, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
western blot
抗MRP5抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Cell Lines
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Proteins
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esiRNA
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