HomeSmall Molecule HPLCAscentis® Express RP-Amide Columns for HPLC and UHPLC

Ascentis® Express RP-Amide Columns for HPLC and UHPLC

Improved separation of basic compounds

While the Ascentis® Express C8 and C18 provide classic reversed-phase selectivity, the RP-Amide phase provides alternate reversed-phase selectivity:

  • Improved peak shape for basic compounds
  • 100% aqueous compatibility
  • LC-MS compatibility
  • Fast separation with Fused-Core® technology

The Ascentis® Express RP-Amide HPLC column provides increased selectivity for polar compounds, especially those that can act as a hydrogen bond donor.

Featured Application

RP-Amide phase with Fused-Core® particles for fast separation of basic compounds

Ascentis® Express RP-Amide is a high-speed, high-performance liquid chromatography column based on a superficially porous Fused-Core® particle design. The Fused-Core® particle provides a thin porous shell of high-purity silica surrounding a solid silica core. This particle design exhibits very high column efficiency due to the shallow diffusion paths. Three different particle sizes are available for your specific needs:

2.0 µm particles

Best Fused-Core UHPLC Column

An optimized solution for high-throughput small molecule analysis

2.7 µm particles

Fast HPLC on ANY System

A practical solution that delivers UHPLC performance from any HPLC

5.0 µm particles

The Lab Work-Horse Column

True plug and play solution for improving existing 3 or 5 µm fully porous particle HPLC columns

HPLC Guard Column