- Musashi-1 promotes a cancer stem cell lineage and chemoresistance in colorectal cancer cells.
Musashi-1 promotes a cancer stem cell lineage and chemoresistance in colorectal cancer cells.
Scientific reports (2017-05-21)
Guang-Yuh Chiou, Tzu-Wei Yang, Chi-Chou Huang, Chia-Ying Tang, Jung-Yi Yen, Ming-Chang Tsai, Hsuan-Yi Chen, Nurul Fadhilah, Chun-Che Lin, Yuh-Jyh Jong
PMID28526879
ABSTRACT
Colorectal cancers (CRCs) are a critical health issue worldwide. Cancer stem cell (CSC) lineages are associated with tumour transformation, progression, and malignant transformation. However, how lineages are transformed and how chemoresistance is acquired by CRCs remain largely unknown. In this report, we demonstrated that the RNA-binding protein Musashi-1 enhanced the development of CD44
MATERIALS
Product Number
Brand
Product Description
Sigma-Aldrich
Monoclonal Anti-CD44-FITC antibody produced in mouse, clone MEM-85, purified immunoglobulin, buffered aqueous solution
Millipore
ANTI-FLAG® antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution
Sigma-Aldrich
Monoclonal ANTI-FLAG® M2 antibody produced in mouse, clone M2, purified immunoglobulin (Purified IgG1 subclass), buffered aqueous solution (10 mM sodium phosphate, 150 mM NaCl, pH 7.4, containing 0.02% sodium azide)