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  • Polypyrrole nanotubes conjugated with human olfactory receptors: high-performance transducers for FET-type bioelectronic noses.

Polypyrrole nanotubes conjugated with human olfactory receptors: high-performance transducers for FET-type bioelectronic noses.

Angewandte Chemie (International ed. in English) (2009-03-11)
Hyeonseok Yoon, Sang Hun Lee, Oh Seok Kwon, Hyun Seok Song, Eun Hae Oh, Tai Hyun Park, Jyongsik Jang
ABSTRACT

Get a whiff of this: Human olfactory receptor (hOR)-conjugated polypyrrole (PPy) nanotubes were integrated into the field-effect transistor (FET) sensor platform for the fabrication of high-performance bioelectronic noses (see picture, S = source, D = drain). The device can translate and amplify hOR-odorant interaction into a detectable signal, and it showed highly sensitive and specific responses toward a target odorant.

MATERIALS
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Sigma-Aldrich
Amyl butyrate, ≥98%, FG