Search Within
Content Type
Applied Filters:
Applications:Reaction design and optimization
Content Type:Technical Article
Showing 1-30 of 134 results
Use of 13C Isotopes
Dr. Pratip Bhattacharya, California Institute of Technology. "Stable isotopes have played a very useful role in MR research which involves both MRI and MRS.
Scale-Up Guide: Photocatalysis Reaction
Scale-Up Guide for Photocatalysis Reaction to best enable scale-up success with High-Throughput Screening Kit.
Aldol Condensation Reaction
The aldol condensation reaction is an organic reaction introduced by Charles Wurtz, who first prepared the β-hydroxy aldehyde from acetaldehdye in 1872.
Inverse Electron Demand Diels–Alder Reactions of 1,2,4,5-Tetrazines and 1,2,3-Triazines
The inverse electron demand Diels-Alder reactions of electron-deficient heterocycles are significant cycloaddition reactions for the total synthesis of natural products containing highly substituted and functionalized heteroaromatic ring systems.
New Aromatic Terminal Alkynes
The terminal alkyne functionality has a wide range of applications including most recently the synthesis of spiropyran substituted 2,3-dicyanopyrazines and (±)-asteriscanolide, as well as conversion to enamines using resin-bound 2° amines.
Potassium Organotrifluoroborates
These bench stable Potassium Organotrifluoroborates are useful for Suzuki-Miyaura cross-coupling reactions and have also been used for a variety of other C-C bond forming reactions. Importantly, these reagents are compatible with a wide range of functional groups and are...
Trialkylphosphine for Morita-Baylis Hillman Reactions
The use of amines and phosphines in nucleophilic catalysis is well precedented; however, arguably one of the severe limitations with respect to exploiting the more nucleophilic, yet less basic, phosphine in this regard is its air sensitivity.
(+)-Sparteine Surrogate presents an article concerning (+)-Sparteine Surrogate.
The use of CBILS© – Carbonate Based Ionic Liquid Synthesis – developed by the Austrian company proionic, offers one of the simplest, yet most elegant synthetic methods for the production of ionic liquids
QuinoxP*: Air-Stable and Highly Efficient and Productive Chiral Ligands
Jacobsen Thioureas
Jacobsen’s group has developed a range of chiral thioureas that are versatile and effective organocatalysts. A range of latent nucleophiles can be added to mostly imine-type electrophiles in excellent enantiomeric excesses and, in general, with a broad substrate scope.
Hydrogenation Catalysts and Ligands
We are proud to offer new catalysts for hydrogenation through our collaboration with Kanata Chemical Technologies.
Oxazolidinone Chiral Auxiliaries
Oxazolidinone chiral auxiliaries are often used for diastereoselective Michael additions, alkylations, aldol condensations, cyclopropanations, Diels-Alder, and other reactions. We operates 29 manufacturing facilities globally to supply your development and scale-up needs.
Molecular Sieves
Molecular sieves are crystalline metal aluminosilicates having a threedimensional interconnecting network of silica and alumina tetrahedra. Natural water of hydration is removed from this network by heating to produce uniform cavities which selectively adsorb molecules of a specific size.
Selective Metalation, Deprotonation, and Additions
Transformative reagents for selective metalation, deprotonation and nucleophilic additions have allowed for unprecedented selective converstions to reactive intermediates within a molecule which contains sensative functionalities under mild reactions.
Selective Metalations
Selective Metalations using i-PrMgCl·LiCl and s-BuMgCl·LiCl
N-Heterocyclic Carbene Ligands
A wide range of NHC ligands are commonly available which exhibit high activities.
Azide Building Blocks for Chemical Ligation
Chemoselective ligation strategies are a key success factor for chemical biology research. Ligation techniques open pathways to fully synthetic large peptides and even proteins.
Continuous Flow Synthesis in Microstructured Reactors — A New Way of Thinking Chemical Synthesis
Continuous Flow Synthesis in Microstructured Reactors — A New Way of Thinking Chemical Synthesis
Red-Al® Reducing Agent
Red-Al®, or sodium bis(2-methoxyethoxy)aluminum dihydride (Vitride®, SMEAH), is a versatile reducing agent and a good substitute for LiAlH4 in many reactions. Red-Al® is nonpyrophoric, although still moisture-sensitive, and is available in solution, allowing for easier handling compared to LiAlH4.
Redi-Dri™ – The world of free-flowing hygroscopic products
Redi-Dri™ prevents hygroscopic powders, such as inorganic salts, from absorbing moisture and forming clumps, leaving the salts free-flowing every time.
BASIL™—BASF’s Processes Based on Ionic Liquids
The most important application of Ionic Liquids described is their use as reaction media for chemical processes. A major breakthrough was reached with BASF’s introduction of the first application on a commercial scale: the BASIL™-process.
Facile and Rapid Chiral Resolution with ChiroSolv Kits
Our company is pleased to partner with ChiroSolve, Inc. to offer, through an exclusive distribution agreement, a series of ready-to-use kits for chiral resolution of racemates.
Chiral Alcohols
Chiral Alcohols
SyTracks Carbon Monoxide Generator FAQs
What is COgen? What is COware? What is the SyTracks COgenerator system? And more questions answered.
Greener Methods: Catalytic Amide Bond Formation
We are proud to offer a number of products used in catalytic amidation technology.
Trichloroacetimidate Reagents
Trichloroacetimidates are also commonly employed as alcohol alkylation reagents, particularly when existing functionality is not acid sensitive.
Drying Agents
Many products such as aluminas, silicas and molecular sieves can be employed as reasonably effective drying agents which can usually be conveniently regenerated. Current chemical literature reflects an active interest in the drying process, and even the method by which...
Solvent Stabilizer Systems
A description of stabilizer systems for solvents including esters, ethyl ester, tetrahydrofuran, chlorinated solvents, chloroform and dichloromethane.
Hartmann and co-workers have described the synthesis of a series of potent and selective inhibitors of aldosterone synthase (CYP11B2), in which the key synthetic step was a Wittig reaction using various heterocyclic aldehydes.
Page 1 of 5
Page 1 of 5