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Baeyer-Villiger Oxidation Reaction
The Baeyer-Villiger oxidation is the oxidative cleavage of a carbon-carbon bond adjacent to a carbonyl, which converts the ketones to esters and the cyclic ketones to lactones.
Ugi Reaction
The Ugi reaction (Scheme 1) is an isonitrile-based MCR that provides a rapid route for the preparation of a-aminoacyl amide derivatives. The Ugi 4 component condensation of an amine, oxo compound, carboxylic acid and an isocyanide is the most documented
Biginelli Reaction
The Biginelli Reaction is an acid catalyzed, threecomponent reaction between an aldehyde, b-ketoester, and urea that produces tetrahydropyrimidones, which have potential pharmaceutical applications.
Reagents for the Mitsunobu Reaction
One of the most powerful and widely used carboncarbon bond forming reactions in organic synthesis is the Mitsunobu reaction.
Aldehydes - Types & Structure
Technical article regarding Aldehydes - Types & Structure
Periodic Table of the Elements
Download the Periodic Table of the Elements with names, atomic mass and number in printable .pdf and image format. Use the periodic table chart by element names in alphabetical order for quick research, reference and lab use. From MilliporeSigma.
Knoevenagel Condensation Reaction
Knoevenagel Condensation is an organic reaction named after Emil Knoevenagel. It is a classic C-C bond formation reaction and a modification of the Aldol Condensation.
Synthia™ Organic Retrosynthesis Software - Resources
Learn more about Synthia™ Organic Retrosynthesis Software and view a list of publications
Friedel–Crafts Acylation
The Friedel–Crafts acylation is the reaction of an arene with acyl chlorides or anhydrides using a strong Lewis acid catalyst. This reaction proceeds via electrophilic aromatic substitution to form monoacylated products.
Spirocyclic Building Blocks for Scaffold Assembly
Spirocyclic modules containing four-membered rings are currently of growing interest to discovery chemists.
Protected Carbohydrate Building Blocks for More Efficient Syntheses
Carbohydrates and their biologically active glycoconjugate analogs are emerging as an important class of biomolecules.
Fries Rearrangement
The Fries rearrangement reaction is an organic name reaction which involves the conversion of phenolic esters into hydroxyaryl ketones on heating in the presence of a catalyst. Suitable catalysts for this reaction are Brønsted or Lewis acids such as HF
1-hydrosilatrane
As a versatile hydride reagent, 1-hydrosilatrane can be used in reduction reactions to synthesize alcohols, amines, their chiral counterparts, and esters from aldehydes/ketones.
Diels–Alder Reaction
The Diels–Alder reaction is the reaction between a conjugated diene and an alkene (dienophile) to form unsaturated six-membered rings. Since the reaction involves the formation of a cyclic product via a cyclic transition state, it is also referred to as
Unnatural Amino Acids
Unnatural amino acids, the non-proteinogenic amino acids that either occur naturally or are chemically synthesized, are becoming more and more important as tools for modern drug discovery research.
Inverse Electron Demand Diels–Alder Reactions of 1,2,4,5-Tetrazines and 1,2,3-Triazines
The inverse electron demand Diels-Alder reactions of electron-deficient heterocycles are significant cycloaddition reactions for the total synthesis of natural products containing highly substituted and functionalized heteroaromatic ring systems.
Schlenk Type Glassware
This system is specifically designed for additions, chemical reactions, distillations, drying/evaporation, extractions, filtrations, recrystallizations, washing, degassing, and transfers of solids and liquids.
Aldol Condensation Reaction
The aldol condensation reaction is an organic reaction introduced by Charles Wurtz, who first prepared the β-hydroxy aldehyde from acetaldehdye in 1872.
VSEPR Chart | Valence Shell Electron Pair Repulsion Theory
Use our handy VSEPR chart to find the 3-D geometric VSEPR shapes of molecules and ions. Learn about VSEPR theory and shapes like trigonal planar or square pyramidal. VSEPR stands for valence shell electron pair repulsion.
Heck Reaction Applications & Products
The Heck reaction is the palladium catalyzed cross-coupling reaction between alkenes and aryl or vinyl halides (or triflates) to afford substituted alkenes.