Merck
Search Within
Applications
Content Type
Applied Filters:
Applications:Cancer research
Content Type:Technical Article
Showing 1-30 of 41 results
Sort by Relevance
Epigenetics Overview
Epigenetics is a term coined to describe changes that are not mutation based but can still be passed on from generation to generation. Genes that are activated or repressed without any change in DNA sequence are epigenetically controlled. Epigenetic modifications
Vitamin D and Prevention of Human Disease
Vitamin D2 (ergocalciferol) is naturally synthesized from ergosterol by invertebrates, fungi, and plants in response to ultraviolet B irradiation, while vitamin D3 synthesis (cholecalciferol) is uniquely initiated in the skin of vertebrates. During sun exposure, ultraviolet B photons are absorbed
DNA Damage and Repair
DNA damage and repair mechanism is vital for maintaining DNA integrity. Damage to cellular DNA is involved in mutagenesis, the development of cancer among others.
Autophagy Mitophagy in Tumor Cell Survival Death
Autophagy is a highly regulated process that is involved in cell growth, development, and death. In autophagy cells destroy their own cytoplasmic components in a very systematic manner and recycle them.
ABC Transporters and Cancer Drug Resistance
We presents an article on ABC Transporters and Cancer Drug Resistance
Prestige Antibodies® in Breast Cancer Research
The Human Protein Atlas; Prestige Antibodies®; Polyclonals and Monoclonals; Clinical Markers; Antibodies used in Breast Cancer Research; Antibodies Against MammaPrint and Other Gene Expression Test Proteins; Antibodies Identified in the Human Protein Atlas; Finding Cancer Biomarkers, as Exemplified by RBM3
Ginseng (Panax quinquefolius) Augments Doxorubicin-Induced Inhibition of Human Breast Cancer Cell Proliferation and Tumor Growth: Mechanisms of Action
Ginseng root extract inhibits the proliferation of human cancer cells in vitro, including those that represent many common cancers, such as breast cancer. Ginseng extracts contain over 20 different ginsenosides, saponin glycosides that are biologically active constituents of ginseng. Several
Glutamine Metabolism is Dysregulated in Many Cancer Cells
Sigma-Aldrich presents an article about how proliferatively active cells require both a source of carbon and of nitrogen for the synthesis of macromolecules. Although a large proportion of tumor cells utilize aerobic glycolysis and shunt metabolites away from mitochondrial oxidative
Autophagy in Cancer Promotes Therapeutic Resistance
We presents an article on Autophagy in Cancer Promotes Therapeutic Resistance
Fatty Acid Synthesis and Metabolism in Cancer Cells
Information on fatty acid synthesis and metabolism in cancer cells. Learn how proliferatively active cells require fatty acids for functions such as membrane generation, protein modification, and bioenergetic requirements. These fatty acids are derived either from dietary sources or are
Overview of Cancer Biology
We deliver the broadest selection available of carcinogenic and chemopreventive biochemicals, as well as research reagents and kits for apoptosis, angiogenesis, biomarker identification, metabolomics, and functional genomics.
Superoxide Dismutase
Enzyme Explorer Product Application Index for Superoxide Dismutase offered by us online. Superoxide Dismutase (SOD) catalyzes the reduction of superoxide anions to hydrogen peroxide.
Epidermal growth factor receptor (EGFR) signaling
Read review on EGF/EGFR signaling (epidermal growth factor receptor) and find links to related products at sigmaaldrich.com
Dynamic Live Cell Imaging of Caspase Mediated Apoptosis and Cellular Hypoxia in Lymphocytes and Cancer Cells Using the CellASIC® ONIX2 Microfluidic Platform
Application note on how the CellASIC® ONIX2 microfluidic system can be used to analyze caspase-3 mediated apoptosis/cell death and cellular hypoxia in live immune and cancer cell lines.
Primary Cell Culture Basics
What are primary cells? A comprehensive overview of animal and human primary cell lines and media and how they are used in biomedical cell culture applications. Primary cultures are less homogeneous relative to cell lines.
Carcinogenesis and Epigenetics
Carcinogenesis and Epigenetics
Co-culture of Tumor and Stromal Cells in TrueGel3D™ Hydrogels
TrueGel3D™ synthetic hydrogel can be used to study co-culture of tumor and stromal cells.
Long-Term Live Cell Tracking of Cancer and Stem Cells Using a Biocompatible Fluorescent Nanoparticle Based Upon Aggregation Induced Emission (AIE Dot) Nanotechnology
Biocompatible organic fluorescent nanoparticles (AIE Dots) that can be used to label cells and vasculature for long-term live cell tracking and tracing experiments.
Applications of Cytokines and Growth Factors in Cancer Research
Applications of Cytokines and Growth Factors in Cancer Research
Fibroblast Growth Factor Family (FGF)
Fibroblast growth factors in cell culture and various growth factors for your research
Apoptosis Assays
Cellular apoptosis assays to detect programmed cell death using Annexin V, Caspase and TUNEL DNA fragmentation assays.
Immunohistochemistry: Current Applications in Breast Cancer
Immunohistochemistry (IHC) is used to characterize intracellular proteins or various cell surfaces in all tissues. Individual markers or more often panels of various marker proteins can be used to characterize various tumor subtypes, confirm tissue of origin, distinguish metastatic from
Folic Acid Metabolism in Cancer
This issue of Biofiles reviews some of our newest and most innovative technologies and their specific applications toward cancer research. In preparing this issue of Biofiles, one is reminded how complex the disease of cancer is, and how difficult it
Folic Acid Metabolism: A Role in Cancer's Cause and Cure
This article reviews some of our newest and most innovative technologies and their specific applications toward cancer research. It describes how complex the disease of cancer is, and how difficult it is to identify one topic that is completely
TokeOni: Properties and Applications
Bioluminescence imaging (BLI) systems allows for high-sensitive and noninvasive monitoring of cell proliferation, activity of signaling pathways and protein-protein interactions in living tissues.
Nucleotide Synthesis in Cancer Cells
Neoplastic cells are highly dependent on the de novo synthesis of nucleotides to maintain sufficient pools to support DNA replication and the production of RNA.
Comet Assay
The Comet Assay, also called single cell gel electrophoresis (SCGE), is a sensitive and rapid technique for quantifying and analyzing DNA damage in individual cells.
Epigenetic Mechanisms in Cancer Pathogenesis
This page reviews some of our newest and most innovative technologies and their specific applications toward cancer research. One is reminded of how complex the disease of cancer is, and how difficult it is to identify one topic that is
Hypoxia Detection Assays
Hypoxia detection assays to measure oxygen levels in both live and fixed cells and tissues.
Cell Migration & Invasion Assays
Metastasis is the cumulative result of multiple changes in tumor cells. Explore tumor metastasis employing various cell migration and invasion assays like Boyden chamber assay, Millicell® µ-Migration Assay and in vitro scratch assay.
Page 1 of 2
Page 1 of 2