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United States Pharmacopeia (USP) Reference Standard

,5-Cyclohexadiene-1,4-dione, Quinone, p-Benzoquinone
Linear Formula:
CAS Number:
Molecular Weight:
MDL number:
PubChem Substance ID:


pharmaceutical primary standard

vapor density

3.73 (vs air)

vapor pressure

0.1 mmHg ( 25 °C)

autoignition temp.

815 °F




113-115 °C (lit.)


pharmaceutical (small molecule)



SMILES string




InChI key


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General description

1,4-Benzoquinone, also known as para-quinone, is a benzene derivative with cyclic dienedione structure.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia.


The USP pharmaceutical reference standard is intended for use in analytical or laboratory applications as specified in USP compendia.

Also ideal for use as a primary reference standard in the following tests or assays according to USP General Chapter <11>:

  • pure steam
  • water for injection
  • sterile water for inhalation
  • sterile water for injection
  • sterile water for irrigation
  • purified water
  • sterile purified water
  • water for hemodialysis
  • <643>total organic carbon

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

USP issued SDS can be found here.
Sales restrictions may apply.

Signal Word


Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Flam. Sol. 1 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

4.1B - Flammable solid hazardous materials



Flash Point(F)

170.6 °F - closed cup

Flash Point(C)

77 °C - closed cup

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More Documents

Quotes and Ordering

Electrochemical detoxification of a 1, 4-benzoquinone solution in wastewater treatment.
Pulgarin, Cesar, et al.
Water Research, 28.4, 887-893 (1994)
Oliver Karge et al.
Biochimica et biophysica acta, 1837(10), 1625-1634 (2014-07-27)
The functional or regulatory role of long-distance interactions between protein surface and interior represents an insufficiently understood aspect of protein function. Cationic screening of surface charges determines the morphology of thylakoid membrane stacks. We show that it also influences directly
Rajaram Venkatesan et al.
Nature communications, 5, 4805-4805 (2014-09-10)
Mitochondrial fatty acid synthesis (mtFAS) is essential for respiratory growth in yeast and mammalian embryonic survival. The human 3-ketoacyl-acyl carrier protein (ACP) reductase (KAR) of mtFAS is a heterotetrameric α2β2-assembly composed of 17β-hydroxysteroid dehydrogenase type-8 (HSD17B8, α-subunit) and carbonyl reductase
Hui Dong et al.
Chemico-biological interactions, 212, 47-55 (2014-02-08)
Our previous study has demonstrated that PCB quinone is cytotoxic in HepG2 cells (Toxicology in Vitro 26 (2012) 841-848). However, it is not clear whether PCB quinone is also carcinogenic (or mutagenic). In the current study, we investigated the genotoxicity
Cheuk-Kwan Sun et al.
Journal of pineal research, 58(2), 137-150 (2014-12-11)
Despite high in-hospital mortality associated with acute respiratory distress syndrome (ARDS), there is no effective therapeutic strategy. We tested the hypothesis that combined melatonin-mitochondria treatment ameliorates 100% oxygen-induced ARDS in rats. Adult male Sprague-Dawley rats (n = 40) were equally categorized into

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