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Visiprep SPE Vacuum Manifold

DL (Disposable Liner), 24-port model

Quality Level


PTFE frit
polypropylene tube

product line



solid phase extraction (SPE): suitable


food and beverages

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General description

The Visiprep DL (Disposable Liner) Vacuum Manifold eliminates the possibility of cross-contamination when processing a new sample on the same port. The liner consists of a PP female luer hub that attaches to the SPE, and thin-walled PTFE tubing that is threaded through the SPE port. This ensures that all SPE port and valve surfaces coming in contact with the sample can be replaced following each extraction.
SPE is a form of chromatography, and, as with other chromatographic techniques, control of flow rate is critical for maintaining reproducible extractions. Unlike other vacuum manifolds, the Visiprep system contains a patented valve system that allows for precise flow control through each SPE tube via rotating, independent, screw-type valves situated in each port within the manifold cover. Visiprep vacuum manifolds allow you to process up to 12 (12-port version) or 24 (24-port version) SPE samples simultaneously. Spacing between ports are slightly smaller on the 24-port versions than the 12-port versions so consideration of tube sizes is recommended.


Visiprep SPE Vacuum Manifold was used to perform solid phase extraction to separate polyphenols from grapes, in order to determine the polyphenol content using LC-MS analysis. It was also used for concentration and purification of solvent extracts from surface water and sewage water sediments. Furthermore it was also used to extract and determine estrone in water using solid-phase extraction-enzyme-linked immunosorbent assay (SPE-ELISA).

Features and Benefits

Supplied with 100 disposable liners (Part No. 57059).
  • Patented screw-type valves within each SPE port for precise flow control
  • Glass basin will not dissolve, fog, or discolor when exposed to solvents
  • Legs on cover allow user to easily rest cover on work surface when removed from the manifold
  • Screw-type solvent-resistant vacuum bleed gauge and valve offer better sealing and vacuum control. Valve takes 1/4″ vacuum tubing.
  • PP collection vessel rack accommodates autosampler vials; small scintillation vials (22.75 mm O.D. recommended); 10 and 16 mm test tubes; and 1, 2, 5, and 10 mL volumetric flasks. An optional plate for 20 mL scintillation vials is available for 12-port models.

Legal Information

Visiprep is a trademark of Sigma-Aldrich Co. LLC

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. Can I convert the Visiprep DL 24-port Manifold, Product No. 57265, to a Standard 24-port Manifold, Product No. 57250-U?

    Yes, by replacing the manifold lid with Product No. 57251 or by replacing some of the DL ports to standard ports with Product No. 57032 and Product No. 57147-U

  4. What is the maximum vacuum for the Visiprep Vacuum Manifold, Product 57265?

    The maximum vacuum for the Visiprep Vacuum Manifold is 20 inches of Mercury (Hg).

  5. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  6. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  7. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Guangdi Wang et al.
Journal of environmental monitoring : JEM, 14(5), 1353-1364 (2012-03-23)
Endocrine disrupting compounds (EDCs), represented by steroid hormones, organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), and bisphenol A have been determined in four sediment cores from the Gulf of Mexico, from New Orleans surface water (Lake Pontchartrain and Mississippi River), and
Angeles M Alonso Borbalán et al.
Journal of chromatography. A, 1012(1), 31-38 (2003-09-26)
There is considerable interest in the analysis of phenolic compounds due to their involvement in the organoleptic characteristics of foods and drinks, and their contribution to protection against cardiovascular diseases and cancers through their antioxidant activity. This article describes studies
Development of a solid-phase extraction-enzyme-linked immunosorbent assay method for the determination of estrone in water.
Li, Zhilan, et al.
Analytica Chimica Acta, 503, 171-177 (2004)


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Related Content

Solid Phase Extraction (SPE)

Solid phase extraction (SPE) is a technique used for rapid, selective sample preparation and purification prior to chromatographic analysis (e.g. HPLC, GC, TLC). SPE is used to exchange sample matrices, concentrate analytes, and remove interferences and contaminants to improve data and protect the analytical column.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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