RAB0960

Phosphotyrosine FER / Tyrosine-protein Kinase Fer ELISA Kit

• UNSPSC Code: 41116158
• NACRES: NA.32

Properties

• species reactivity: human
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable
• input: sample type: human cell lysate
• assay range: inter-assay cv: <10%; intra-assay cv: <12%
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... FER(2241)

Description

General description

FER (fps/fes related) tyrosine kinase is encoded by the gene mapped to human chromosome 5q21.3. Tyrosine kinase is a cytoplasmic protein characterized with a single SH2 domain and an extensive amino terminus. The encoded protein is ubiquitously expressed.

The antibody pair provided in this kit recognizes Human Tyrosine-Phosphorylated-FER.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

FER tyrosine kinase induces signal transduction at the plasma membrane. It is implicated in the regulation of cell-cell adhesion. FER tyrosine kinase interacts with phosphatidic acid (PA) to enhance phosphorylation of cortactin, a protein that promotes actin.

Kit Components Also Available Separately

• RABHRP6 Phosphotyrosine ELISA HRP-Streptavidin

Safety Information

• Pictograms: GHS05
• Signal Word: Warning
• Hazard Statements: H290
• Precautionary Statements: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Storage Class Code: 8A - Combustible, corrosive hazardous materials
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable