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GW22597F

Sigma-Aldrich

Anti-S100A6 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

MDL number:
MFCD00677384
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

chicken

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, rat, human

technique(s)

western blot: suitable

NCBI accession no.

NP_055439.1

UniProt accession no.

P06703

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... S100A6(6277)

General description

Protein S100-A6 is a homodimeric protein encoded by the S100A6 gene in humans. It is a member of S100 protein family. It is involved in several biological functions such as cell proliferation, differentiation, morphology, cytoskeletal organization and apoptosis.

Immunogen

Immunogen Sequence: GI # 7657532, sequence 1-90
Recombinant S100 calcium-binding protein A6

Application

Anti-S100A6 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Protein S100-A6 is a homodimeric protein encoded by the S100A6 gene in humans and is a member of S100 protein family. It has biological functions in cell proliferation, differentiation, morphology, cytoskeletal organization and apoptosis. S100A6 plays an important role in regulating endothelial commitment to, and progression through, the cell cycle. It is involved in several vital biological functions, such as calcium sensing and cell proliferation. S100A6 helps in promoting proliferation and migration of human hepatoma cells. Overexpression results in alteration of E-cadherin and β-catenin and is over expressed in human hepatocellular carcinoma.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

GW22597F-VAR:
GW22597F-BULK:
GW22597F-50UG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ziqiang Li et al.
Journal of molecular medicine (Berlin, Germany), 92(3), 291-303 (2013-11-28)
High levels of S100A6 have been associated with poor outcome in some types of human cancers, but the role of S100A6 in the molecular pathogenesis of these cancers is largely unknown. This study was performed to explore the expression and
Leyuan Bao et al.
The FEBS journal, 279(24), 4576-4588 (2012-10-26)
Endothelial cells regulate many aspects of vascular physiology, including vasculogenesis and angiogenesis. The S100 family of calcium-binding proteins regulates many aspects of cell function but their roles in vascular physiology are less well understood. Herein, we investigated the expression and
Sepuru K Mohan et al.
Biochemical and biophysical research communications, 434(2), 328-333 (2013-03-30)
S100A6 is involved in several vital biological functions, such as calcium sensing and cell proliferation. It is a homodimeric protein that belongs to the S100 protein family. The receptor for advanced glycation end products (RAGE) has been shown to play
Honglin He et al.
Protein expression and purification, 83(1), 98-103 (2012-03-28)
S100A6, as a member of S100 protein family, have biological functions in cell proliferation, differentiation, morphology, cytoskeletal organization and apoptosis. In the last three decades, S100A6 has been caught more and more attention. Here, we introduced a simple and efficient

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