23186

Fmoc chloride

for HPLC derivatization, LiChropur^™, ≥99.0% (HPLC)

• Synonym(s): 9-Fluorenylmethoxycarbonyl chloride, 9-Fluorenylmethyl chloroformate, Fmoc-Cl
• Empirical Formula (Hill Notation): C₁₅H₁₁ClO₂
• CAS Number: 28920-43-6
• Molecular Weight: 258.70
• Beilstein: 2279177
• EC Number: 249-313-6
• MDL number: MFCD00001138
• PubChem Substance ID: 329752393
• NACRES: NA.22

Properties

• grade: for HPLC derivatization
• Quality Level: 100
• assay: ≥99.0% (HPLC)
• form: solid
• quality: LiChropur^™
• technique(s): HPLC: suitable
• mp: 61-64 °C; 62-64 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: ClC(=O)OCC1c2ccccc2-c3ccccc13
• InChI: 1S/C15H11ClO2/c16-15(17)18-9-14-12-7-3-1-5-10(12)11-6-2-4-8-13(11)14/h1-8,14H,9H2
• InChI key: IRXSLJNXXZKURP-UHFFFAOYSA-N

Description

General description

Fmoc chloride is a derivatizing agent.

Application

Fmoc chloride may be used as derivatizing reagent in pre-column derivatization of the biogenic amines, resolved using HPLC technique.[1]

Reagent for derivatizing amino acids for HPLC amino acid analysis and for preparing N-Fmoc amino acids for solid-phase peptide synthesis.

Other Notes

Reagent for precolumn derivatization of amines for HPLC and fluorescent detection (abs.: 265 nm, em.: 315 nm)[2][3][4]; Used for capillary electrophoresis[5]

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Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Supplementary Hazards: EUH029
• Storage Class Code: 8A - Combustible, corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves