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Safety Information

MAB366

Sigma-Aldrich

Anti-MAP1B Antibody, clone AA6

ascites fluid, clone AA6, Chemicon®

Synonym(s):

MAP5

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

ascites fluid

antibody product type

primary antibodies

clone

AA6, monoclonal

species reactivity

feline, chicken, hamster, rat, bovine, mouse

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NM_005909.3
NM_032010.1

UniProt accession no.

P46821

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... MAP1B(4131)

Specificity

Reacts specifically with MAP1B (MAP5) by immunoblot. Shows selective staining of dendritic trees throughout the brain. No cross-reactivity observed to other MAPs or tubulin.

Monoclonal Anti-MAP1b is immunospecific for MAP1b (also known as MAP5, MAPIX or MAP1.2; Riederer et al., 1986; Tucker et al., 1988) as determined by an immunoblot assay. Addition of antibody to microtubule proteins before polymerization results in abnormally short (but otherwise morphologically normal) microtubules.

Immunogen

Rat brain microtubule-associated protein.

Application

Anti-MAP1B Antibody, clone AA6 detects level of MAP1B & has been published & validated for use in WB, IH.
Immunoblotting at 1:300-1:500.

Immunohistochemistry

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Neurofilament & Neuron Metabolism

Physical form

Ascites. Liquid containing 15mM sodium azide.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

MAB366:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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B Pattnaik et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 20(18), 6789-6796 (2000-09-21)
Protein MAP1B was recently reported to link GABA(C) receptors to the cytoskeleton at neuronal synapses. This interaction was demonstrated in the mammalian retina, where GABA(C) receptors were thought to be exclusively expressed in bipolar cells. Our previous studies on cultured
B Riederer et al.
Journal of neurocytology, 15(6), 763-775 (1986-12-01)
A novel microtubule-associated protein, MAP5, is described, whose chemical properties and cytological distribution distinguish it from other known microtubule-associated proteins (MAPs). Its status as a MAP is indicated by the observations that (i) it co-assembles efficiently with microtubules in vitro
Samer Swedan et al.
Journal of virology, 85(19), 10090-10100 (2011-07-29)
Human respiratory syncytial virus (RSV), a major cause of severe respiratory diseases, efficiently suppresses cellular innate immunity, represented by type I interferon (IFN), using its two unique nonstructural proteins, NS1 and NS2. In a search for their mechanism, NS1 was
R P Tucker et al.
The Journal of comparative neurology, 271(1), 44-55 (1988-05-01)
We have used monoclonal antibodies to study the distribution of three developmentally regulated microtubule-associated proteins-MAP2, MAP5, and tau-during the morphogenesis of the thoracic spinal cord and peripheral nervous system in the quail. MAP5 is the only one of the three
Proteins released from degenerating neurons are surrogate markers for acute brain damage.
Robert Siman, Tracy K McIntosh, Kristie M Soltesz, Zhaoming Chen, Robert W Neumar et al.
Neurobiology of Disease null
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