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Key Documents

Safety Information

07-1815

Sigma-Aldrich

Anti-FIP200 Antibody

serum, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, rat, mouse

technique(s)

western blot: suitable

UniProt accession no.

Q86YR4

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

rat ... Stx8(59074)

General description

Focal adhesion kinase family interacting protein of 200 kDa (FIP200) is a novel protein inhibitor for focal adhesion kinase (FAK). FIP200 inhibits kinase activity and associated cellular functions, such as cell adhesion, spreading, and motility in fibroblasts by binding directly to FAK.

Specificity

This antibody recognizes the C-terminal region of FIP200.

Immunogen

Epitope: C-terminus
The immunogen was a synthetic peptide corresponding to the C-terminal region of FIP200.

Application

Detect FIP200 using this Anti-FIP200 Antibody validated for use in WB.
Research Category
Signaling
Research Sub Category
PI3K, Akt, & mTOR Signaling

Quality

Evaluated by western blot on HEK293 cell lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody was used to detect FIP200 in HEK293 cell lysate.

Target description

200 kDa

Physical form

Unpurified rabbit serum in buffer containing 0.05% sodium azide.

Storage and Stability

Stable for 2 years at -20°C from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

07-1815:

Certificates of Analysis (COA)

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Zhengwei Ma et al.
The Journal of clinical investigation, 130(9), 5011-5026 (2020-08-18)
Dysregulation of autophagy in diabetic kidney disease (DKD) has been reported, but the underlying mechanism and its pathogenic role remain elusive. We show that autophagy was inhibited in DKD models and in human diabetic kidneys. Ablation of autophagy-related gene 7

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