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Key Documents

Safety Information

D-145

Supelco

N-Desmethylclobazam solution

1.0 mg/mL (acetonitrile:DMSO (90:10 v/v)), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C15H11ClN2O2
CAS Number:
Molecular Weight:
286.71
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL (acetonitrile:DMSO (90:10 v/v))

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

InChI

1S/C15H11ClN2O2/c16-10-6-7-12-13(8-10)18(11-4-2-1-3-5-11)15(20)9-14(19)17-12/h1-8H,9H2,(H,17,19)

InChI key

RRTVVRIFVKKTJK-UHFFFAOYSA-N

General description

Ephedrine is a methamphetamine analog commonly used as a stimulant and appetite suppressant. It is also found as an active constituent in herbs used for traditional Chinese medicine, such as má huáng. This certified reference standard can be used Snap-N-Spike® as a starting material in the preparation of calibrators or controls for clinical or forensic applications or Snap-N-Shoot® in quality control testing of dietary supplements containing ephedrine.

Application


  • N-Desmethylclobazam metabolite research applications: N-Desmethylclobazam is a critical metabolite in the pharmacokinetic studies of clobazam, used for understanding its biotransformation and elimination patterns in the body. This knowledge is vital for optimizing dosing regimens in clinical settings, particularly for treating conditions like epilepsy (Tomasini et al., 1985).

  • Clobazam impurity profiling in pharmaceutical analysis: The analysis of N-Desmethylclobazam is essential in impurity profiling where it serves as a marker for the purity and stability of clobazam formulations. This application is crucial in regulatory compliance and quality control of pharmaceutical products (Kunicki, 2001).

  • N-Desmethylclobazam reference standard for bioanalytical method development: Used extensively as a reference standard in the development of bioanalytical methods, N-Desmethylclobazam enables accurate and reliable quantification of clobazam and its metabolites in biological samples, supporting clinical and forensic investigations (Levy et al., 1983).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2.0 °C - closed cup


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

D-145-1ML:4548173350257


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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