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860533P

Avanti

C16 Ceramide-1-Phosphate (d18:1/16:0)

Avanti Research™ - A Croda Brand 860533P, powder

Synonym(s):

N-palmitoyl-ceramide-1-phosphate (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C34H71N2O6P
CAS Number:
1246303-22-9
Molecular Weight:
634.91
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 mg (860533P-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860533P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)COP([O-])(O)=O.[NH4+]

General description

C16 Ceramide-1-Phosphate (d18:1/16:0) or N-palmitoyl-ceramide-1-phosphate is a natural long chain ceramide.

Application

C16 Ceramide-1-Phosphate (d18:1/16:0) or N-palmitoyl-ceramide-1-phosphate has been used in lipid preparation to treat endothelial colony-forming cells (ECFCs) for nuclear morphology analysis. It has also been used as a bioactive lipid in cell migration assay to study its effects on multipotent stromal cell (MSCs) and human umbilical vein endothelial cells (HUVECs).

Packaging

5 mL Amber Glass Screw Cap Vial (860533P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

860533P-VAR:
860533P-1MG:
860533P-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hebe Agustina Mena et al.
Arteriosclerosis, thrombosis, and vascular biology, 39(10), e219-e232 (2019-08-23)
Ceramide 1-phosphate (C1P) is a bioactive sphingolipid highly augmented in damaged tissues. Because of its abilities to stimulate migration of murine bone marrow-derived progenitor cells, it has been suggested that C1P might be involved in tissue regeneration. In the present
V T Hinkovska-Galcheva et al.
The Journal of biological chemistry, 273(50), 33203-33209 (1998-12-05)
Ceramide, a product of agonist-stimulated sphingomyelinase activation, is known to be generated during the phagocytosis of antibody-coated erythrocytes by polymorphonuclear leukocytes. Agonist-stimulated formation of ceramide-1-phosphate is now shown to occur in 32PO4-labeled neutrophils. Ceramide-1-phosphate is formed by a calcium-dependent ceramide
Antonio Gómez-Muñoz et al.
Journal of lipid research, 45(1), 99-105 (2003-10-03)
It was reported previously that ceramide-1-phosphate (Cer-1-P) is mitogenic for fibroblasts (Gómez-Muñoz, A., P. A. Duffy, A. Martin, L. O'Brien, H-S. Byun, R. Bittman, and D. N. Brindley. 1995. Mol. Pharmacol. 47: 883-889; Gómez-Muñoz, A., L. M. Frago, L. Alvarez
A Gomez-Muñoz et al.
Molecular pharmacology, 47(5), 833-839 (1995-05-01)
Ceramide and ceramide-1-phosphate are sphingolipid analogues of diacylglycerol and phosphatidate, respectively, and they are putative second messengers of agonist-stimulated sphingomyelin metabolism. The interactions of exogenous cell-permeable ceramides and ceramide-1-phosphates in modifying DNA synthesis and signal transduction were investigated in Rat-1

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